MULTISPECIES: DNA polymerase III subunit beta [Klebsiella].

LOCUS       WP_004151533             366 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_004151533
VERSION     WP_004151533.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 366)
  AUTHORS   McGrath,A.E., Martyn,A.P., Whittell,L.R., Dawes,F.E., Beck,J.L.,
            Dixon,N.E., Kelso,M.J. and Oakley,A.J.
  TITLE     Crystal structures and biochemical characterization of DNA sliding
            clamps from three Gram-negative bacterial pathogens
  JOURNAL   J Struct Biol 204 (3), 396-405 (2018)
   PUBMED   30366028
  REMARK    Erratum:[J Struct Biol. 2019 Aug 1;207(2):234. PMID: 31097372]
REFERENCE   2  (residues 1 to 366)
  AUTHORS   Gui,W.J., Lin,S.Q., Chen,Y.Y., Zhang,X.E., Bi,L.J. and Jiang,T.
  TITLE     Crystal structure of DNA polymerase III beta sliding clamp from
            Mycobacterium tuberculosis
  JOURNAL   Biochem Biophys Res Commun 405 (2), 272-277 (2011)
   PUBMED   21219854
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00663.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..366
                     /gene="dnaN"
     Protein         1..366
                     /product="DNA polymerase III subunit beta"
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /calculated_mol_wt=40377
     Region          1..366
                     /region_name="PRK05643"
                     /note="DNA polymerase III subunit beta; Validated"
                     /db_xref="CDD:235541"
     Site            order(24,73,80,198)
                     /site_type="other"
                     /note="putative DNA binding surface [nucleotide binding]"
                     /db_xref="CDD:238082"
     Site            order(74,77,103,105,272,303..304)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238082"
     Site            order(172,174..177,320,362..365)
                     /site_type="active"
                     /note="beta-clamp/clamp loader binding surface [active]"
                     /db_xref="CDD:238082"
     Site            order(172,174..175,247,282,295..296,323,362..365)
                     /site_type="active"
                     /note="beta-clamp/translesion DNA polymerase binding
                     surface [active]"
                     /db_xref="CDD:238082"
ORIGIN      
        1 mkftverehl lkplqqvsgp lggrptlpil gnlllqvaeg alsltgtdle memvarvalv
       61 qpheagattv parkffdicr glpegaeiav qlegdrmlvr sgrsrfslst lpaadfpnld
      121 dwqseveftl pqatmkrlie atqfsmahqd vryylngmlf etegselrtv atdghrlavc
      181 smpleaslpn hsvivprkgv ielmrmldgg diplrvqigs nnirahvgdf iftsklvdgr
      241 fpdyrrvlpk npdkhleagc dilkqafara ailsnekfrg vrlyvsenql kitannpeqe
      301 eaeeildvty agtemeigfn vsyvldvlna lkcenvrill tdsvssvqie daasqsaayv
      361 vmpmrl