MULTISPECIES: iron-containing alcohol dehydrogenase [Klebsiella].

LOCUS       WP_004151427             382 aa            linear   BCT 21-MAR-2023
ACCESSION   WP_004151427
VERSION     WP_004151427.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 382)
  AUTHORS   Shanbhag,A.P., Ghatak,A. and Rajagopal,S.
  TITLE     Industrial light at the end of the iron-containing (group III)
            alcohol dehydrogenase tunnel
  JOURNAL   Biotechnol Appl Biochem (2022) In press
   PUBMED   35751426
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (residues 1 to 382)
  AUTHORS   Carpenter,E.P., Hawkins,A.R., Frost,J.W. and Brown,K.A.
  TITLE     Structure of dehydroquinate synthase reveals an active site capable
            of multistep catalysis
  JOURNAL   Nature 394 (6690), 299-302 (1998)
   PUBMED   9685163
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10169378
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..382
                     /product="iron-containing alcohol dehydrogenase"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=40165
     Region          10..378
                     /region_name="Fe-ADH-like"
                     /note="Iron-containing alcohol dehydrogenases-like;
                     cd08183"
                     /db_xref="CDD:341462"
     Site            order(39,93..95,98,101,138..139,141,160..161,179,187,194,
                     198,262,266,276)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341462"
     Site            order(194,198,262,276)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:341462"
ORIGIN      
        1 mltpftvlmp anirfgrgqa esaapwlaqq ggpillvhga spqraaflrq qletlqlavt
       61 tlaisrepwl sdieqgvqla rekgiravvs lgggavidag kaiaalvpaa gpvidylevv
      121 gtgrqleasp lpfvaiptta gtgaeatkna vinvpeqqrk vslrddrmlp dlaivdpalt
      181 dnaprsitls sgldaltqvi epwlcsratp ftdalcqqai prgiralkil meqecpasrd
      241 emawvslcgg lalanaglgv ihglagplgg lsrashgalc gsllpfglal nesqindpgl
      301 rqrvndvrrw ladgldvpvd rvwdslrews hraglgtlrd lgvardalep aalaastsss
      361 mkanpvslsg eqllemleaa we