MULTISPECIES: 4-hydroxy-tetrahydrodipicolinate reductase

LOCUS       WP_004151369             273 aa            linear   BCT 29-APR-2021
            [Klebsiella].
ACCESSION   WP_004151369
VERSION     WP_004151369.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 273)
  AUTHORS   Scapin,G., Reddy,S.G., Zheng,R. and Blanchard,J.S.
  TITLE     Three-dimensional structure of Escherichia coli dihydrodipicolinate
            reductase in complex with NADH and the inhibitor
            2,6-pyridinedicarboxylate
  JOURNAL   Biochemistry 36 (49), 15081-15088 (1997)
   PUBMED   9398235
REFERENCE   2  (residues 1 to 273)
  AUTHORS   Pavelka,M.S. Jr., Weisbrod,T.R. and Jacobs,W.R. Jr.
  TITLE     Cloning of the dapB gene, encoding dihydrodipicolinate reductase,
            from Mycobacterium tuberculosis
  JOURNAL   J Bacteriol 179 (8), 2777-2782 (1997)
   PUBMED   9098082
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00036.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..273
                     /gene="dapB"
     Protein         1..273
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /EC_number="1.17.1.8"
                     /GO_function="GO:0008839 -
                     4-hydroxy-tetrahydrodipicolinate reductase [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=28517
     Region          6..268
                     /region_name="DapB"
                     /note="4-hydroxy-tetrahydrodipicolinate reductase [Amino
                     acid transport and metabolism]; COG0289"
                     /db_xref="CDD:440058"
ORIGIN      
        1 mhdaqirvai agaggrmgrq liqaalqmeg valgaalere gsslvgsdag elagagkagv
       61 avqsslaavk ddfdvlidft rpegtlnhla fcrehgkgmv igttgfddag kqairdaaqd
      121 iaivfaanfs vgvnvllkll ekaakvmgdy tdieiieahh rhkvdapsgt alamgeaiag
      181 alnkdlkdca vysregytge rvpgtigfat vragdivgeh tamfadiger ieithkassr
      241 mtfangavrs alwlkgkkng lfdmrdvldl nsl