MULTISPECIES: glycine betaine/L-proline ABC transporter permease

LOCUS       WP_004151038             355 aa            linear   BCT 17-JUL-2023
            ProW [Klebsiella].
ACCESSION   WP_004151038
VERSION     WP_004151038.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 355)
  AUTHORS   Wang,S., Fang,Y., Wang,Z., Zhang,S., Wang,L., Guo,Y. and Wang,X.
  TITLE     Improving L-threonine production in Escherichia coli by elimination
            of transporters ProP and ProVWX
  JOURNAL   Microb Cell Fact 20 (1), 58 (2021)
   PUBMED   33653345
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 355)
  AUTHORS   Stirling,D.A., Hulton,C.S., Waddell,L., Park,S.F., Stewart,G.S.,
            Booth,I.R. and Higgins,C.F.
  TITLE     Molecular characterization of the proU loci of Salmonella
            typhimurium and Escherichia coli encoding osmoregulated glycine
            betaine transport systems
  JOURNAL   Mol Microbiol 3 (8), 1025-1038 (1989)
   PUBMED   2691838
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008196.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10952
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..355
                     /gene="proW"
     Protein         1..355
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=37492
     Region          1..355
                     /region_name="PRK10952"
                     /note="proline/glycine betaine ABC transporter permease
                     ProW"
                     /db_xref="CDD:236805"
     Site            order(162..163,166..167,172,181..184,186..195,198..199,
                     201,217..218,220,222,225..226,228,232..233,236,253,
                     267..268,271,278..281,284..285,298..299,309..310,313..314,
                     316..317,320..321)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:119394"
     Site            order(187..201,278..283)
                     /site_type="active"
                     /note="conserved gate region [active]"
                     /db_xref="CDD:119394"
     Site            order(201,212,284,296,299,309)
                     /site_type="active"
                     /note="putative PBP binding loops [active]"
                     /db_xref="CDD:119394"
     Site            order(237..249,255..256,260)
                     /site_type="active"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119394"
ORIGIN      
        1 madqtnpwgs apstdsaaqa adawggasta apangggadw lhsapapqpe qfnimdpfhk
       61 tlipldswvt haidwivlhf rplfqgirvp idyilsafqq lllgipapva iivfaliawq
      121 isslgmgvat lvsliaigai gawsqamvtl alvltallfc mviglplgiw larspraaki
      181 irplldamqt tpafvylvpi vmlfgignvp gvvvtiifal ppivrltilg inqvpadlie
      241 asrsfgaspr qllfkvqlpl amptimagvn qtlmlalsmv viasmiavgg lgqmvlrgig
      301 rldmglatvg gvgivilaii ldrltqavgr darsrgnrrw yttgplglit rpfcr