MULTISPECIES: 1,3-propanediol dehydrogenase [Enterobacteriaceae].

LOCUS       WP_004150927             387 aa            linear   BCT 29-JUL-2023
ACCESSION   WP_004150927
VERSION     WP_004150927.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   Oh,B.R., Seo,J.W., Heo,S.Y., Luo,L.H., Hong,W.K., Park,D.H. and
            Kim,C.H.
  TITLE     Efficient production of 1,3-propanediol from glycerol upon
            constitutive expression of the 1,3-propanediol oxidoreductase gene
            in engineered Klebsiella pneumoniae with elimination of by-product
            formation
  JOURNAL   Bioprocess Biosyst Eng 36 (6), 757-763 (2013)
   PUBMED   23361186
REFERENCE   2  (residues 1 to 387)
  AUTHORS   Qi,X., Deng,W., Wang,F., Guo,Q., Chen,H., Wang,L., He,X. and
            Huang,R.
  TITLE     Molecular cloning, co-expression, and characterization of glycerol
            dehydratase and 1,3-propanediol dehydrogenase from Citrobacter
            freundii
  JOURNAL   Mol. Biotechnol. 54 (2), 469-474 (2013)
   PUBMED   22821086
REFERENCE   3  (residues 1 to 387)
  AUTHORS   Zhuge,B., Zhang,C., Fang,H., Zhuge,J. and Permaul,K.
  TITLE     Expression of 1,3-propanediol oxidoreductase and its isoenzyme in
            Klebsiella pneumoniae for bioconversion of glycerol into
            1,3-propanediol
  JOURNAL   Appl. Microbiol. Biotechnol. 87 (6), 2177-2184 (2010)
   PUBMED   20499228
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012274
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..387
                     /gene="dhaT"
     Protein         1..387
                     /product="1,3-propanediol dehydrogenase"
                     /EC_number="1.1.1.202"
                     /calculated_mol_wt=41335
     Region          6..384
                     /region_name="PDDH"
                     /note="1,3-Propanediol (1,3-PD) dehydrogenase; cd08188"
                     /db_xref="CDD:341467"
     Site            order(41,101..103,106,109,142..143,145,164..165,183,191,
                     198,202,267,271,281)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341467"
     Site            order(198,202,267,281,285)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:341467"
ORIGIN      
        1 msyrmfdylv pnvnffgpna isvvgercql lggkkallvt dkglraikdg avdktlhylr
       61 eagievaifd gvepnpkdtn vrdglavfrr eqcdiivtvg ggsphdcgkg igiaathegd
      121 lyqyagietl tnplppivav nttagtasev trhcvltnte tkvkfvivsw rnlpsvsind
      181 pllmigkpaa ltaatgmdal thaveayisk danpvtdaaa mqairliarn lrqavalgsn
      241 lqarenmaya sllagmafnn anlgyvhama hqlgglydmp hgvanavllp hvarynlian
      301 pekfadiael mgenitglst ldaaekaiaa itrlsmdigi pqhlrdlgvk eadfpymaem
      361 alkdgnafsn prkgneqeia aifrqaf