MULTISPECIES: cystathionine beta-lyase [Klebsiella].

LOCUS       WP_004149836             395 aa            linear   BCT 07-MAY-2024
ACCESSION   WP_004149836
VERSION     WP_004149836.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005990.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08114
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..395
                     /gene="metC"
     Protein         1..395
                     /product="cystathionine beta-lyase"
                     /EC_number="4.4.1.13"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /calculated_mol_wt=43061
     Region          1..395
                     /region_name="PRK08114"
                     /note="cystathionine beta-lyase; Provisional"
                     /db_xref="CDD:181231"
     Site            order(30..33,35..36,56,58,84..85,87..88,111,116,119,209,
                     217,219,235,245,247..248,329)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(85..87,111,154,185,207,209..210,219)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(85..87,111,185,188,207,209..210)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            210
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
ORIGIN      
        1 madkhldtal vnagrskkyt qgsvnsviqr asslvfdtve akkhatrnra ngelfygrrg
       61 tlthfslqea mceleggagc alfpcgaaav antilafveq gdhvlmtnta yepsqdfctk
      121 ilaklgvtts wfdpligadi arlvrpetrv vflespgsit mevhdvpaiv aavrqvapea
      181 iimidntwaa gilfkaldfg idisiqagtk ylighsdamv gtavanarcw pqlrenaylm
      241 gqmldadtay mtsrglrtlg vrlrqhhess lriaewlaqh pqvarvnhpa lpgskghefw
      301 krdftgssgl fsfvlskrln daelaeyldn fslfsmaysw ggfeslilan qpeqiahirp
      361 daevdfsgtl irlhiglenv ddlqadlaag fariv