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LOCUS WP_004148478 305 aa linear BCT 01-JAN-2025 ACCESSION WP_004148478 VERSION WP_004148478.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 305) AUTHORS Qu,Z. and Hartzell,H.C. TITLE Bestrophin Cl- channels are highly permeable to HCO3- JOURNAL Am J Physiol Cell Physiol 294 (6), C1371-C1377 (2008) PUBMED 18400985 REFERENCE 2 (residues 1 to 305) AUTHORS Tsunenari,T., Sun,H., Williams,J., Cahill,H., Smallwood,P., Yau,K.W. and Nathans,J. TITLE Structure-function analysis of the bestrophin family of anion channels JOURNAL J Biol Chem 278 (42), 41114-41125 (2003) PUBMED 12907679 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10007980 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..305 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..305 /product="bestrophin family protein" /GO_function="GO:0005254 - chloride channel activity [Evidence IEA]" /calculated_mol_wt=34772 Region 1..302 /region_name="YneE" /note="Predicted membrane chloride channel, bestrophin family [Inorganic ion transport and metabolism]; COG3781" /db_xref="CDD:442995" ORIGIN 1 miirpeqhwf lrlfdwhgsv lskiifrlll nvlmsiiaii syqwyeqlgi hltvapfsll 61 giaiaiflgf rnsasysrfv earnlwgtvl iaertlvrql rnilpaehda hrrivsylva 121 fswslkhqlr ktdptadlrr llpeervtei lassmptnri lllagneigq lreagklsdi 181 tyglmdnkld elahvlggce rlattpvpfa ytlilqrtvy lfctllpfal vgdlhymtpf 241 vsvfisytfl swdslaeele dpfgtaandl plnamcntie rnlldmtgqh plpetlrpdr 301 yfnlt