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MULTISPECIES: bestrophin family protein [Klebsiella].


LOCUS       WP_004148478             305 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004148478
VERSION     WP_004148478.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 305)
  AUTHORS   Qu,Z. and Hartzell,H.C.
  TITLE     Bestrophin Cl- channels are highly permeable to HCO3-
  JOURNAL   Am J Physiol Cell Physiol 294 (6), C1371-C1377 (2008)
   PUBMED   18400985
REFERENCE   2  (residues 1 to 305)
  AUTHORS   Tsunenari,T., Sun,H., Williams,J., Cahill,H., Smallwood,P.,
            Yau,K.W. and Nathans,J.
  TITLE     Structure-function analysis of the bestrophin family of anion
            channels
  JOURNAL   J Biol Chem 278 (42), 41114-41125 (2003)
   PUBMED   12907679
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007980
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..305
                     /product="bestrophin family protein"
                     /GO_function="GO:0005254 - chloride channel activity
                     [Evidence IEA]"
                     /calculated_mol_wt=34772
     Region          1..302
                     /region_name="YneE"
                     /note="Predicted membrane chloride channel, bestrophin
                     family [Inorganic ion transport and metabolism]; COG3781"
                     /db_xref="CDD:442995"
ORIGIN      
        1 miirpeqhwf lrlfdwhgsv lskiifrlll nvlmsiiaii syqwyeqlgi hltvapfsll
       61 giaiaiflgf rnsasysrfv earnlwgtvl iaertlvrql rnilpaehda hrrivsylva
      121 fswslkhqlr ktdptadlrr llpeervtei lassmptnri lllagneigq lreagklsdi
      181 tyglmdnkld elahvlggce rlattpvpfa ytlilqrtvy lfctllpfal vgdlhymtpf
      241 vsvfisytfl swdslaeele dpfgtaandl plnamcntie rnlldmtgqh plpetlrpdr
      301 yfnlt