MULTISPECIES: 4-aminobutyrate--2-oxoglutarate transaminase

LOCUS       WP_004147193             427 aa            linear   BCT 06-NOV-2024
            [Klebsiella].
ACCESSION   WP_004147193
VERSION     WP_004147193.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005985.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08088
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..427
                     /gene="gabT"
     Protein         1..427
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /EC_number="2.6.1.19"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009448 - gamma-aminobutyric acid
                     metabolic process [Evidence IEA]"
                     /calculated_mol_wt=45386
     Region          1..425
                     /region_name="PRK08088"
                     /note="4-aminobutyrate--2-oxoglutarate transaminase"
                     /db_xref="CDD:236149"
     Site            order(110..112,138..139,141,206,239,241..242,268)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(111..112,138..139,206,239,242,268)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            268
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 mnsnkammar rsdavprgvg qihpifaera encrvwdveg reyldfaggi avlntghlhp
       61 qvvaavedql kklshtcfqv layepylalc ekmnqkvpgd fakktllvtt gseavenavk
      121 iaraatgrsg aiaftgayhg rthytlsltg kvnpysagmg lmpghvyral ypcalhgvsd
      181 deaiasihri fkndaapedi aaiiiepvqg eggfyaaspa fmqrlralcd ehgimliade
      241 vqsgagrtgt lfameqmgva adittfaksi aggfplagvt graevmdaia pgglggtyag
      301 npiacaaala vlqifeqenl lekanqlgdt lrqgllaiae dhpeigdvrg lgamiaielf
      361 eegdrsrpna rltadivara rdkglillsc gpyynvlril vpltieeaqi eqglkiiadc
      421 fseakqa