MULTISPECIES: homoserine O-acetyltransferase MetA [Klebsiella].

LOCUS       WP_004146576             309 aa            linear   BCT 13-JAN-2025
ACCESSION   WP_004146576
VERSION     WP_004146576.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 309)
  AUTHORS   Bastard,K., Perret,A., Mariage,A., Bessonnet,T., Pinet-Turpault,A.,
            Petit,J.L., Darii,E., Bazire,P., Vergne-Vaxelaire,C., Brewee,C.,
            Debard,A., Pellouin,V., Besnard-Gonnet,M., Artiguenave,F.,
            Medigue,C., Vallenet,D., Danchin,A., Zaparucha,A., Weissenbach,J.,
            Salanoubat,M. and de Berardinis,V.
  TITLE     Parallel evolution of non-homologous isofunctional enzymes in
            methionine biosynthesis
  JOURNAL   Nat Chem Biol 13 (8), 858-866 (2017)
   PUBMED   28581482
  REMARK    Erratum:[Nat Chem Biol. 2017 Sep 19;13(10):1137. doi:
            10.1038/nchembio1017-1137c. PMID: 28926556]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047918.2
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..309
                     /gene="metA"
     Protein         1..309
                     /product="homoserine O-acetyltransferase MetA"
                     /EC_number="2.3.1.31"
                     /GO_function="GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35561
     Region          1..302
                     /region_name="PRK05368"
                     /note="homoserine O-succinyltransferase; Provisional"
                     /db_xref="CDD:235433"
     Site            47
                     /site_type="active"
                     /note="proposed active site lysine [active]"
                     /db_xref="CDD:153225"
     Site            142
                     /site_type="active"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153225"
ORIGIN      
        1 mpirvqdelp avnflrnenv fvmtttratt qeirplkvli lnlmpkkiet enqflrllsn
       61 splqvdiqll ridaresrnt paehlnnfyc nfdeicdqnf dglivtgapl glvefndvay
      121 wpqikqvlew akdhvtstlf vcwavqaaln ilygipkqtr aekisgvyeh hilhphallt
      181 rgfddsflap hsryadfpag lirdytdlei laeteegday lfaskdkria fvtghpeyda
      241 ntlaseyfrd veaglnpeip hnyfpqndpq nkpratwrsh gnllfanwln yyvyqitpyd
      301 lrhmnptle