MULTISPECIES: 2-iminoacetate synthase ThiH [Klebsiella].

LOCUS       WP_004146303             377 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_004146303
VERSION     WP_004146303.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 377)
  AUTHORS   Leonardi,R. and Roach,P.L.
  TITLE     Thiamine biosynthesis in Escherichia coli: in vitro reconstitution
            of the thiazole synthase activity
  JOURNAL   J Biol Chem 279 (17), 17054-17062 (2004)
   PUBMED   14757766
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02351.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..377
                     /gene="thiH"
     Protein         1..377
                     /product="2-iminoacetate synthase ThiH"
                     /GO_function="GO:0005506 - iron ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=42938
     Region          3..368
                     /region_name="thiH"
                     /note="thiazole biosynthesis protein ThiH; TIGR02351"
                     /db_xref="CDD:131404"
ORIGIN      
        1 mktfsdrwrq lewddirlri nsktaadver alaakqltrd dmmallspaa anyleplaqr
       61 aqrltrqrfg ntvsfyvply lsnlcandct ycgfsmsnri krktldaaei arecaairnl
      121 gfehlllvtg ehqgkvgmdy frqhlpairs qfaslhmevq plateeyael ktlgldgvmv
      181 yqetyhesmy akhhlkgkkq dffwrldtpd rlgaagidki glgaliglsd swrvdcfiva
      241 ehllwlqqry wrsrysvsfp rlrpcaggie paslmderql vqticafrll apevelslst
      301 respwfrdrv iplainnvsa fsktqpggya ddhpeleqfa phddrrpeev asalaarglq
      361 pvwkdwdswl grasqts