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MULTISPECIES: D-sedoheptulose 7-phosphate isomerase [Klebsiella].


LOCUS       WP_004145825             193 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_004145825
VERSION     WP_004145825.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 193)
  AUTHORS   Brooke,J.S. and Valvano,M.A.
  TITLE     Molecular cloning of the Haemophilus influenzae gmhA (lpcA) gene
            encoding a phosphoheptose isomerase required for
            lipooligosaccharide biosynthesis
  JOURNAL   J. Bacteriol. 178 (11), 3339-3341 (1996)
   PUBMED   8655517
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF001628.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00414
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..193
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..193
                     /gene="lpcA"
     Protein         1..193
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /EC_number="5.3.1.28"
                     /GO_function="GO:0008968 - D-sedoheptulose 7-phosphate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:1901135 - carbohydrate derivative
                     metabolic process [Evidence IEA]"
                     /calculated_mol_wt=20741
     Region          1..192
                     /region_name="gmhA"
                     /note="D-sedoheptulose 7-phosphate isomerase; PRK00414"
                     /db_xref="CDD:179012"
     Site            order(13,17,31,34,54,60..61,172..173,177,180,184,188)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:240139"
     Site            order(52..54,119..121,124,167,172)
                     /site_type="active"
                     /db_xref="CDD:240139"
ORIGIN      
        1 myqdlirnel neaaetlanf lqdeanihai qraavllads fkaggkvlsc gnggshcdam
       61 hfaeeltgry renrpgypai aisdvshlsc vsndfgyeyv fsryvesvgr agdvllgist
      121 sgnsgnvika ieaaraqgmk vitltgkdgg kmagsadvei rvphfgyadr iqeihikvih
      181 ilimliekem akg