LytR/AlgR family response regulator transcription factor

LOCUS       WP_004145587             250 aa            linear   BCT 24-DEC-2024
            [Klebsiella pneumoniae].
ACCESSION   WP_004145587
VERSION     WP_004145587.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 250)
  AUTHORS   Gao,R., Bouillet,S. and Stock,A.M.
  TITLE     Structural Basis of Response Regulator Function
  JOURNAL   Annu Rev Microbiol 73, 175-197 (2019)
   PUBMED   31100988
REFERENCE   2  (residues 1 to 250)
  AUTHORS   Behr,S., Heermann,R. and Jung,K.
  TITLE     Insights into the DNA-binding mechanism of a LytTR-type
            transcription regulator
  JOURNAL   Biosci Rep 36 (2), e00326 (2016)
   PUBMED   27013338
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 250)
  AUTHORS   Galperin,M.Y.
  TITLE     Diversity of structure and function of response regulator output
            domains
  JOURNAL   Curr Opin Microbiol 13 (2), 150-159 (2010)
   PUBMED   20226724
REFERENCE   4  (residues 1 to 250)
  AUTHORS   Galperin,M.Y.
  TITLE     Telling bacteria: do not LytTR
  JOURNAL   Structure 16 (5), 657-659 (2008)
   PUBMED   18462668
REFERENCE   5  (residues 1 to 250)
  AUTHORS   Galperin,M.Y.
  TITLE     Structural classification of bacterial response regulators:
            diversity of output domains and domain combinations
  JOURNAL   J Bacteriol 188 (12), 4169-4182 (2006)
   PUBMED   16740923
REFERENCE   6  (residues 1 to 250)
  AUTHORS   Nikolskaya,A.N. and Galperin,M.Y.
  TITLE     A novel type of conserved DNA-binding domain in the transcriptional
            regulators of the AlgR/AgrA/LytR family
  JOURNAL   Nucleic Acids Res 30 (11), 2453-2459 (2002)
   PUBMED   12034833
REFERENCE   7  (residues 1 to 250)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11461715
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..250
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..250
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /calculated_mol_wt=29082
     Region          5..247
                     /region_name="LytT"
                     /note="DNA-binding response regulator, LytR/AlgR family
                     [Transcription, Signal transduction mechanisms]; COG3279"
                     /db_xref="CDD:442510"
ORIGIN      
        1 msgekmkvii vedeflaqqe lswlinthsq meivgsfddg ldvlkflqhn kvdaifldin
       61 ipsldgvlla qnisqfahkp fivfitawke haveafelea fdyilkpyqe sriinmlqkl
      121 ttawqqqnna asglasaapr endtinlikd eriivtsihd iyyaeahekm tfvytrresf
      181 vmpmnitefc sklptahffr chrsycvnls kireiepwfn ntyvlrlrdl efqvpvsrsk
      241 vkefrqlmnl