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ribonuclease PH [Klebsiella pneumoniae].


LOCUS       WP_004145273             251 aa            linear   BCT 24-MAY-2024
ACCESSION   WP_004145273
VERSION     WP_004145273.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 251)
  AUTHORS   Harlow,L.S., Kadziola,A., Jensen,K.F. and Larsen,S.
  TITLE     Crystal structure of the phosphorolytic exoribonuclease RNase PH
            from Bacillus subtilis and implications for its quaternary
            structure and tRNA binding
  JOURNAL   Protein Sci 13 (3), 668-677 (2004)
   PUBMED   14767080
REFERENCE   2  (residues 1 to 251)
  AUTHORS   Kelly,K.O. and Deutscher,M.P.
  TITLE     Characterization of Escherichia coli RNase PH
  JOURNAL   J Biol Chem 267 (24), 17153-17158 (1992)
   PUBMED   1512253
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01966.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..251
                     /gene="rph"
     Protein         1..251
                     /product="ribonuclease PH"
                     /EC_number="2.7.7.56"
                     /GO_function="GO:0000049 - tRNA binding [Evidence IEA]"
                     /GO_function="GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /calculated_mol_wt=26745
     Region          14..250
                     /region_name="Rph"
                     /note="Ribonuclease PH [Translation, ribosomal structure
                     and biogenesis]; COG0689"
                     /db_xref="CDD:440453"
ORIGIN      
        1 mrphirfkpe isimrpagrs anqvrpvtlt rnytkhaegs vlvefgdtkv lctasidegv
       61 prflkgqgqg witaeygmlp rsthtrnare aakgkqggrt meiqrliara lraavdlkal
      121 geftitldcd vlqadggtrt asitgacval adalnklvaa gklktnpmkg mvaavsvgiv
      181 ngeaicdley iedsaaetdm nvvmtedgri ievqgtaege pftheelltl lalarggies
      241 iittqkaale n