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MULTISPECIES: NCS2 family permease [Klebsiella].


LOCUS       WP_004145100             445 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004145100
VERSION     WP_004145100.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 445)
  AUTHORS   Koukaki,M., Vlanti,A., Goudela,S., Pantazopoulou,A., Gioule,H.,
            Tournaviti,S. and Diallinas,G.
  TITLE     The nucleobase-ascorbate transporter (NAT) signature motif in UapA
            defines the function of the purine translocation pathway
  JOURNAL   J Mol Biol 350 (3), 499-513 (2005)
   PUBMED   15953615
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10789293
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..445
                     /product="NCS2 family permease"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /calculated_mol_wt=46386
     Region          14..442
                     /region_name="NCS2"
                     /note="Xanthine/guanine/uracil/vitamin C permease
                     GhxP/GhxQ, nucleobase:cation symporter 2 (NCS2) family
                     [Nucleotide transport and metabolism]; COG2252"
                     /db_xref="CDD:441853"
ORIGIN      
        1 msqqqtsqss gqgllervfk lrehgttvrt eaiagfttfl tmvyivfvnp qilgvagmdt
       61 savfvttcli aafgsilmgl fanlpvalap amglnaffaf vvvqamglpw qvgmgaifwg
      121 avglllltif rvrywmiani plslrvgits giglfigmmg lknagvivan petlvsighl
      181 tshsvllgvl gffiiailas rnihaavlvs ivvttllgwm lgdvhytgiv sappsvasvi
      241 gqvdlagsln lglagvifsf mlvnlfdssg tligvtdkag ladangkfpr mkqalfvdsv
      301 ssvagsfigt ssvtayiess sgvsvggrtg ltavvvgilf llviflspla gmvpgyaaag
      361 aliyvgvlmt sslarvkwsd lteavpafit avmmpfsfsi tegialgfis ycvmkigtgr
      421 lrelspcvii vsllfvlkiv fidah