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LOCUS WP_004144895 447 aa linear BCT 15-SEP-2023 ACCESSION WP_004144895 VERSION WP_004144895.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. REFERENCE 1 (residues 1 to 447) AUTHORS Lemke,C.T. and Howell,P.L. TITLE The 1.6 A crystal structure of E. coli argininosuccinate synthetase suggests a conformational change during catalysis JOURNAL Structure 9 (12), 1153-1164 (2001) PUBMED 11738042 REFERENCE 2 (residues 1 to 447) AUTHORS Lemke,C., Yeung,M. and Howell,P.L. TITLE Expression, purification, crystallization and preliminary X-ray analysis of Escherichia coli argininosuccinate synthetase JOURNAL Acta Crystallogr. D Biol. Crystallogr. 55 (Pt 12), 2028-2030 (1999) PUBMED 10666579 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF003779.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK05370 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..447 /organism="Enterobacteriaceae" /db_xref="taxon:543" gene 1..447 /gene="argG" Protein 1..447 /product="argininosuccinate synthase" /EC_number="6.3.4.5" /GO_function="GO:0004055 - argininosuccinate synthase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0042803 - protein homodimerization activity [Evidence IEA]" /GO_process="GO:0006526 - arginine biosynthetic process [Evidence IEA]" /calculated_mol_wt=49681 Region 1..446 /region_name="PRK05370" /note="argininosuccinate synthase; Validated" /db_xref="CDD:235434" ORIGIN 1 mttilkhlpv gqrigiafsg gldtsaallw mrkkgavpya ytanlgqpde ddydaiprra 61 keygaegarl idcrkqlvae giaaiqcgaf hnttggltyf nttplgravt gtmlvaamke 121 dgvniwgdgs tykgndierf yryglltnae lqiykpwlds dfinelggrh emsefmiacg 181 fdykmsveka ystdsnmlga theakdlefl nssvkivnpi mgvkfwdenv kipaeevtvr 241 feqghpvaln gktfaddvem mleanriggr hglgmsdqie nriieaksrg iyeapgmall 301 hiayerlltg ihnedtieqy hahgrqlgrl lyqgrwfdsq almlrdslqr wvasqitgev 361 tlelrrgndy silntvsdnl tykaerltme kgdsmftaed rigqltmrnl ditdtreklf 421 gyaqsgllsa ssatglpqve nlenkgk