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MULTISPECIES: choline dehydrogenase [Klebsiella].


LOCUS       WP_004142489             554 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_004142489
VERSION     WP_004142489.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 554)
  AUTHORS   Rosenstein,R., Futter-Bryniok,D. and Gotz,F.
  TITLE     The choline-converting pathway in Staphylococcus xylosus C2A:
            genetic and physiological characterization
  JOURNAL   J. Bacteriol. 181 (7), 2273-2278 (1999)
   PUBMED   10094709
REFERENCE   2  (residues 1 to 554)
  AUTHORS   Pocard,J.A., Vincent,N., Boncompagni,E., Smith,L.T., Poggi,M.C. and
            Le Rudulier,D.
  TITLE     Molecular characterization of the bet genes encoding glycine
            betaine synthesis in Sinorhizobium meliloti 102F34
  JOURNAL   Microbiology (Reading, Engl.) 143 (Pt 4), 1369-1379 (1997)
   PUBMED   9141699
REFERENCE   3  (residues 1 to 554)
  AUTHORS   Boch,J., Kempf,B., Schmid,R. and Bremer,E.
  TITLE     Synthesis of the osmoprotectant glycine betaine in Bacillus
            subtilis: characterization of the gbsAB genes
  JOURNAL   J. Bacteriol. 178 (17), 5121-5129 (1996)
   PUBMED   8752328
REFERENCE   4  (residues 1 to 554)
  AUTHORS   van Beilen,J.B., Eggink,G., Enequist,H., Bos,R. and Witholt,B.
  TITLE     DNA sequence determination and functional characterization of the
            OCT-plasmid-encoded alkJKL genes of Pseudomonas oleovorans
  JOURNAL   Mol. Microbiol. 6 (21), 3121-3136 (1992)
   PUBMED   1453953
REFERENCE   5  (residues 1 to 554)
  AUTHORS   Andresen,P.A., Kaasen,I., Styrvold,O.B., Boulnois,G. and Strom,A.R.
  TITLE     Molecular cloning, physical mapping and expression of the bet genes
            governing the osmoregulatory choline-glycine betaine pathway of
            Escherichia coli
  JOURNAL   J. Gen. Microbiol. 134 (6), 1737-1746 (1988)
   PUBMED   3065456
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01810.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..554
                     /gene="betA"
     Protein         1..554
                     /product="choline dehydrogenase"
                     /EC_number="1.1.99.1"
                     /GO_function="GO:0008812 - choline dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /calculated_mol_wt=61419
     Region          1..554
                     /region_name="PRK02106"
                     /note="choline dehydrogenase; Validated"
                     /db_xref="CDD:235000"
ORIGIN      
        1 mqfdyiiiga gsagnvlatr ltedpnttvl lleaggpdyr fdfrtqmpaa layplqgkry
       61 nwayetepep ymnnrrmecg rgkglggssl ingmcyirgn amdldnwake pglehwsyld
      121 clpyyrkaet rdigpndyhg gdgpvsvttp kpgnnplfea mveagvqagy prtddlngyq
      181 qegfgpmdrt vtpqgrrast argyldqarg rpnltirtha ltdhiifagk ravgvewleg
      241 estipskata nkevllcaga iaspqilqrs gvgnpellrq fdipvvhdlp gvgenlqdhl
      301 emylqyecke pvslypalqw wnqpkigaew lfggtgigas nqfeaggfir sraefawpni
      361 qyhflpvain yngsnavkeh gfqchvgsmr spsrghvrlk srdphahpai lfnymsheqd
      421 wqefrdairi treimnqpal dkyrgreisp giecqsdael defvrnhaet afhpcgtckm
      481 gydemavvdg egrvhglegl rvvdasimpq iitgnlnatt imigekmada irgrqplprs
      541 tatyyvagda pvrr