MULTISPECIES: Cof-type HAD-IIB family hydrolase [Klebsiella].

LOCUS       WP_004141971             270 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_004141971
VERSION     WP_004141971.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 270)
  AUTHORS   Leader,D.P. and Milner-White,E.J.
  TITLE     The conserved crown bridge loop at the catalytic centre of enzymes
            of the haloacid dehalogenase superfamily
  JOURNAL   Curr Res Struct Biol 6, 100105 (2023)
   PUBMED   37786806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 270)
  AUTHORS   Yang,L., Lu,Y., Tian,W., Feng,Y., Bai,J. and Zhang,H.
  TITLE     Insights into the functional divergence of the haloacid
            dehalogenase superfamily from phosphomonoesterase to inorganic
            pyrophosphatase
  JOURNAL   Arch Biochem Biophys 705, 108896 (2021)
   PUBMED   33940035
REFERENCE   3  (residues 1 to 270)
  AUTHORS   Burroughs,A.M., Allen,K.N., Dunaway-Mariano,D. and Aravind,L.
  TITLE     Evolutionary genomics of the HAD superfamily: understanding the
            structural adaptations and catalytic diversity in a superfamily of
            phosphoesterases and allied enzymes
  JOURNAL   J Mol Biol 361 (5), 1003-1034 (2006)
   PUBMED   16889794
REFERENCE   4  (residues 1 to 270)
  AUTHORS   Allen,K.N. and Dunaway-Mariano,D.
  TITLE     Phosphoryl group transfer: evolution of a catalytic scaffold
  JOURNAL   Trends Biochem Sci 29 (9), 495-503 (2004)
   PUBMED   15337123
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11576316
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..270
                     /product="Cof-type HAD-IIB family hydrolase"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /calculated_mol_wt=30121
     Region          4..260
                     /region_name="HAD_YbiV-Like"
                     /note="Escherichia coli YbiV sugar
                     phosphatase/phosphotransferase and related proteins;
                     belongs to the haloacid dehalogenase-like superfamily;
                     cd07518"
                     /db_xref="CDD:319820"
     Site            order(9..13,44..46,67,148,150,184,192,214..216,218..219)
                     /site_type="active"
                     /db_xref="CDD:319820"
ORIGIN      
        1 msikliavdm dgtflsdakt ynrprflaqy qrmreqnirf vvasgnqyyq lisffpeiah
       61 qiafvaengg wvvsgnedvf ncqlpvhhfn avvdhlqtlp nieiiacgkr saytlnrynd
      121 alktvaakyy hrlelvddfn hlddtilkfg lnvpdslipe iqpklhaalg dmvtavatgy
      181 gsidliipgv hkanglrilq qrwgiedhev vafgdsgndi emlqhagfgf amanaredvk
      241 avaryqaphn neegvlqiid kvldreapfa