MULTISPECIES: class Ia ribonucleoside-diphosphate reductase subunit

LOCUS       WP_004140835             376 aa            linear   BCT 20-OCT-2023
            beta [Enterobacterales].
ACCESSION   WP_004140835
VERSION     WP_004140835.1
KEYWORDS    RefSeq.
SOURCE      Enterobacterales
  ORGANISM  Enterobacterales
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria.
REFERENCE   1  (residues 1 to 376)
  AUTHORS   Kolberg,M., Strand,K.R., Graff,P. and Andersson,K.K.
  TITLE     Structure, function, and mechanism of ribonucleotide reductases
  JOURNAL   Biochim Biophys Acta 1699 (1-2), 1-34 (2004)
   PUBMED   15158709
REFERENCE   2  (residues 1 to 376)
  AUTHORS   Eriksson,M., Jordan,A. and Eklund,H.
  TITLE     Structure of Salmonella typhimurium nrdF ribonucleotide reductase
            in its oxidized and reduced forms
  JOURNAL   Biochemistry 37 (38), 13359-13369 (1998)
   PUBMED   9748343
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006576.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09101
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterobacterales"
                     /db_xref="taxon:91347"
     gene            1..376
                     /gene="nrdB"
     Protein         1..376
                     /product="class Ia ribonucleoside-diphosphate reductase
                     subunit beta"
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=43376
     Region          1..376
                     /region_name="nrdB"
                     /note="ribonucleotide-diphosphate reductase subunit beta;
                     Reviewed; PRK09101"
                     /db_xref="CDD:181647"
     Site            order(38,45,110..111,114,117..118,121,124,138..139,142)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:153108"
     Site            order(49,85,116,119,123,237..238,242)
                     /site_type="active"
                     /note="putative radical transfer pathway [active]"
                     /db_xref="CDD:153108"
     Site            order(85,116,119,205,239,242)
                     /site_type="other"
                     /note="diiron center [ion binding]"
                     /db_xref="CDD:153108"
     Site            123
                     /site_type="other"
                     /note="tyrosyl radical"
                     /db_xref="CDD:153108"
ORIGIN      
        1 mayttfsqtk ndqllepmff gqpvnvaryd qqkydifekl iekqlsffwr peevdvsrdr
       61 idyqalpehe khifisnlky qtlldsiqgr spnvallpli sipeletwve twafsetihs
      121 rsythiirni vndpatvfdd ivtneqiqkr aegishyyds liemtsywhl lgegthtvng
      181 ktvtvnlrel kkklylclms vnaleairfy vsfacsfafa erklmegnak iirliardea
      241 lhltgtqhml nllrsgsddp emaeiaeeck qecydlfvla aqqekewady lfrdgsmigl
      301 nkdilcqyve yitnirmqav gldlpfqtrs npipwintwl vsdnvqvapq evevssylvg
      361 qidsevdadd lsnfql