MULTISPECIES: spermidine/putrescine ABC transporter

LOCUS       WP_004140590             348 aa            linear   BCT 20-NOV-2023
            substrate-binding protein PotD [Klebsiella].
ACCESSION   WP_004140590
VERSION     WP_004140590.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 348)
  AUTHORS   Igarashi,K. and Kashiwagi,K.
  TITLE     Polyamine transport in bacteria and yeast
  JOURNAL   Biochem J 344 Pt 3, 633-642 (1999)
   PUBMED   10585849
REFERENCE   2  (residues 1 to 348)
  AUTHORS   Johnston,J.S. and Athwal,D.S.
  TITLE     Recombinant anti-polyamine antibodies: identification of a
            conserved binding site motif
  JOURNAL   Protein Eng 12 (6), 515-521 (1999)
   PUBMED   10388849
REFERENCE   3  (residues 1 to 348)
  AUTHORS   Kashiwagi,K., Endo,H., Kobayashi,H., Takio,K. and Igarashi,K.
  TITLE     Spermidine-preferential uptake system in Escherichia coli. ATP
            hydrolysis by PotA protein and its association with membrane
  JOURNAL   J Biol Chem 270 (43), 25377-25382 (1995)
   PUBMED   7592703
REFERENCE   4  (residues 1 to 348)
  AUTHORS   Kashiwagi,K., Miyamoto,S., Nukui,E., Kobayashi,H. and Igarashi,K.
  TITLE     Functions of potA and potD proteins in spermidine-preferential
            uptake system in Escherichia coli
  JOURNAL   J Biol Chem 268 (26), 19358-19363 (1993)
   PUBMED   8366082
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007048.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09501
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..348
                     /gene="potD"
     Protein         1..348
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /EC_number="7.6.2.-"
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0019808 - polyamine binding [Evidence
                     IEA]"
                     /GO_process="GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /calculated_mol_wt=38742
     Region          1..348
                     /region_name="potD"
                     /note="spermidine/putrescine ABC transporter periplasmic
                     substrate-binding protein; Reviewed; PRK09501"
                     /db_xref="CDD:181913"
     Site            order(30,35,40..41,44,55..58,60,216,219..220,235,237)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:270378"
     Site            order(34,229,232,255,257,293)
                     /site_type="other"
                     /note="chemical substrate binding site [chemical binding]"
                     /db_xref="CDD:270378"
ORIGIN      
        1 mkkwsrhlla asalaigmga ahaddsktly fynwteyvpp glleqftket gikviystye
       61 snetmyaklk tykdgaydlv vpstyfvdkm rkegmlqkid kskltnfsnl dpqmlnkpfd
      121 pnndysipyi wgataigvns eaidpktits wadlwkpeyk ssllltddar evfqmalrkl
      181 gysgnttdpk eieaaynelk klmpnvaafn sdnpanpyme gevnlgmvwn gsayvarqag
      241 tpleviwpke ggifwmdsls ipanaknvdg alklinfllr pdvakqvaet igyptpnlaa
      301 rkmlspavan dkslypdaat iekgewqndv gsasaiyeey yqklkagr