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MULTISPECIES: signal peptide peptidase SppA [Klebsiella].


LOCUS       WP_004140411             617 aa            linear   BCT 29-JUN-2020
ACCESSION   WP_004140411
VERSION     WP_004140411.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 617)
  AUTHORS   Ichihara,S., Suzuki,T., Suzuki,M. and Mizushima,S.
  TITLE     Molecular cloning and sequencing of the sppA gene and
            characterization of the encoded protease IV, a signal peptide
            peptidase, of Escherichia coli
  JOURNAL   J. Biol. Chem. 261 (20), 9405-9411 (1986)
   PUBMED   3522590
REFERENCE   2  (residues 1 to 617)
  AUTHORS   Ichihara,S., Beppu,N. and Mizushima,S.
  TITLE     Protease IV, a cytoplasmic membrane protein of Escherichia coli,
            has signal peptide peptidase activity
  JOURNAL   J. Biol. Chem. 259 (15), 9853-9857 (1984)
   PUBMED   6378913
REFERENCE   3  (residues 1 to 617)
  AUTHORS   Pacaud,M.
  TITLE     Purification and characterization of two novel proteolytic enzymes
            in membranes of Escherichia coli. Protease IV and protease V
  JOURNAL   J. Biol. Chem. 257 (8), 4333-4339 (1982)
   PUBMED   7040383
REFERENCE   4  (residues 1 to 617)
  AUTHORS   Regnier,P.
  TITLE     The purification of protease IV of E. coli and the demonstration
            that it is an endoproteolytic enzyme
  JOURNAL   Biochem. Biophys. Res. Commun. 99 (4), 1369-1376 (1981)
   PUBMED   7020700
REFERENCE   5  (residues 1 to 617)
  AUTHORS   Regnier,P.
  TITLE     Identification of protease IV of E, coli
  JOURNAL   Biochem. Biophys. Res. Commun. 99 (3), 844-854 (1981)
   PUBMED   7018496
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008195.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10949
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..617
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..617
                     /gene="sppA"
     Protein         1..617
                     /product="signal peptide peptidase SppA"
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /calculated_mol_wt=66676
     Region          1..617
                     /region_name="PRK10949"
                     /note="signal peptide peptidase SppA"
                     /db_xref="CDD:182860"
ORIGIN      
        1 mrtlwrlias ffkwtwriln firklalnai flvlvlvcig iwsqfsstts ehaargalll
       61 ditgvvvdkp sassklgvig rqlfgassdr lqenslfdiv qtirqakddr nitgivldlk
      121 nfvggdqpsm qyigkalref rdsgkpvyav gssysqgqyy lasfankiwl spqgevdlhg
      181 fatnglyyks lldklkvsth vfrvgtyksa vepfirddms paareadsrw igelwqnyln
      241 tiaanrqita qqlfpgaqgi idglrkvggd takyaldnkl vdelatstev ekaltkqfgw
      301 skadnnyrai syydynvktp sdqgsaiavi fangaimdge etpgnvggdt taaqirdarl
      361 dpkikaivlr vnspggsvta seiireelaa akaagkpvvv smggmaasgg ywistpadyi
      421 vanpstltgs igifgvintv entlgsigvh tdgvatspla dvsstkalpp evqqlmqlsi
      481 engyqrfitl vanarkstpe kidqiaqghv wtgedakang lvdslgdfdd avakaaelak
      541 lktwhlnyyq eeptffsmvl dsltgsvras lpaaiqawlp apvaaaaetv kaesdklaaf
      601 ndpqnryafc ltcanir