MULTISPECIES: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase

LOCUS       WP_004140117             262 aa            linear   BCT 01-JUL-2024
            PaaG [Gammaproteobacteria].
ACCESSION   WP_004140117
VERSION     WP_004140117.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 262)
  AUTHORS   Teufel,R., Mascaraque,V., Ismail,W., Voss,M., Perera,J.,
            Eisenreich,W., Haehnel,W. and Fuchs,G.
  TITLE     Bacterial phenylalanine and phenylacetate catabolic pathway
            revealed
  JOURNAL   Proc Natl Acad Sci U S A 107 (32), 14390-14395 (2010)
   PUBMED   20660314
REFERENCE   2  (residues 1 to 262)
  AUTHORS   Luengo,J.M., Garcia,J.L. and Olivera,E.R.
  TITLE     The phenylacetyl-CoA catabolon: a complex catabolic unit with broad
            biotechnological applications
  JOURNAL   Mol Microbiol 39 (6), 1434-1442 (2001)
   PUBMED   11260461
REFERENCE   3  (residues 1 to 262)
  AUTHORS   Ferrandez,A., Minambres,B., Garcia,B., Olivera,E.R., Luengo,J.M.,
            Garcia,J.L. and Diaz,E.
  TITLE     Catabolism of phenylacetic acid in Escherichia coli.
            Characterization of a new aerobic hybrid pathway
  JOURNAL   J Biol Chem 273 (40), 25974-25986 (1998)
   PUBMED   9748275
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02280.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..262
                     /gene="paaG"
     Protein         1..262
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase PaaG"
                     /EC_number="5.3.3.18"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=27945
     Region          1..262
                     /region_name="PRK08140"
                     /note="enoyl-CoA hydratase; Provisional"
                     /db_xref="CDD:236163"
     Site            order(24,26,58,62..66,109,111..113,135..136,139)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:119339"
     Site            order(64,113)
                     /site_type="active"
                     /note="oxyanion hole (OAH) forming residues [active]"
                     /db_xref="CDD:119339"
     Site            order(93,101,122..125,137..140,146,148..150,152..153,
                     158..159,161..162,164..165,168,179,182,197,200..201)
                     /site_type="other"
                     /note="trimer interface [polypeptide binding]"
                     /db_xref="CDD:119339"
ORIGIN      
        1 meafilsave qgvmtitlnr pdrlnsfndl mhhqlaeclk qaerddgvrc llitgagrgf
       61 cagqdlndrn vdpsgpppdl gmsverfynp lvrrlaalpk pvicavngva agagatlalg
      121 cdivlaarsa kfvmafsklg lvpdcggswf lprvagrara mglallgdsl saeqaaqwgi
      181 iwqlvddsel adtslqlarh laaqptfglg likkallase tnsldaqldl erdyqrlagr
      241 sddyregvsa flakrppqfs gk