MATE family efflux transporter [Listeria monocytogenes].

LOCUS       WP_003738285             446 aa            linear   BCT 27-MAR-2023
ACCESSION   WP_003738285
VERSION     WP_003738285.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 446)
  AUTHORS   Claxton,D.P., Jagessar,K.L. and Mchaourab,H.S.
  TITLE     Principles of Alternating Access in Multidrug and Toxin Extrusion
            (MATE) Transporters
  JOURNAL   J Mol Biol 433 (16), 166959 (2021)
   PUBMED   33774036
REFERENCE   2  (residues 1 to 446)
  AUTHORS   Kusakizako,T., Miyauchi,H., Ishitani,R. and Nureki,O.
  TITLE     Structural biology of the multidrug and toxic compound extrusion
            superfamily transporters
  JOURNAL   Biochim Biophys Acta Biomembr 1862 (12), 183154 (2020)
   PUBMED   31866287
REFERENCE   3  (residues 1 to 446)
  AUTHORS   Radchenko,M., Symersky,J., Nie,R. and Lu,M.
  TITLE     Structural basis for the blockade of MATE multidrug efflux pumps
  JOURNAL   Nat Commun 6, 7995 (2015)
   PUBMED   26246409
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10192092
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..446
                     /product="MATE family efflux transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=48610
     Region          9..445
                     /region_name="MATE_like_8"
                     /note="Uncharacterized subfamily of the multidrug and
                     toxic compound extrusion (MATE) proteins; cd13134"
                     /db_xref="CDD:240539"
ORIGIN      
        1 mssvhkvasi slftlawpif leqflrlmis yidvfmlghy sddavaatgv anqilvisii
       61 iygfisvgvq iivaqmigak khkeienvit nglvvaflig ivmsiififm sknfltwmgi
      121 dphlvqvgap fleiiggssv viaihasilp ilrahgyvrq silvpvtisi invvgnylfl
      181 ygplayldyg vagvgistav anfvgmglai wmlrkyigyt fhfkkleqvs kkllysilrl
      241 glpsagenls yagsqlvvta iiailgteal ttkvyastvs qfvalfaial gqasqiiigr
      301 avgakeidka ykqglrswki glvvaivvsv siylfaepim rlfttnteii amtkelflls
      361 iflelgratn iiiisslnst gdvrfpficg livmwivslp fsyvlgisag lglvgvwlay
      421 iidegvravl myrrwrskvw slksvi