phosphatidylinositol-specific phospholipase C [Listeria

LOCUS       WP_003733144             317 aa            linear   BCT 16-OCT-2019
            monocytogenes].
ACCESSION   WP_003733144
VERSION     WP_003733144.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 317)
  AUTHORS   Mitchell,G., Ge,L., Huang,Q., Chen,C., Kianian,S., Roberts,M.F.,
            Schekman,R. and Portnoy,D.A.
  TITLE     Avoidance of autophagy mediated by PlcA or ActA is required for
            Listeria monocytogenes growth in macrophages
  JOURNAL   Infect. Immun. 83 (5), 2175-2184 (2015)
   PUBMED   25776746
REFERENCE   2  (residues 1 to 317)
  AUTHORS   Camilli,A., Goldfine,H. and Portnoy,D.A.
  TITLE     Listeria monocytogenes mutants lacking
            phosphatidylinositol-specific phospholipase C are avirulent
  JOURNAL   J. Exp. Med. 173 (3), 751-754 (1991)
   PUBMED   1847723
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR010228
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..317
                     /gene="plcA"
     Protein         1..317
                     /product="phosphatidylinositol-specific phospholipase C"
                     /calculated_mol_wt=36187
     Region          51..314
                     /region_name="PI-PLCc"
                     /note="Catalytic domain of prokaryotic and eukaryotic
                     phosphoinositide-specific phospholipase C; cd00137"
                     /db_xref="CDD:176497"
     Site            order(67..68,106,148,199,258)
                     /site_type="active"
                     /db_xref="CDD:176497"
     Site            order(67,115)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:176497"
ORIGIN      
        1 myknylqrtl vlllcfilyf ftfplggkay slnnwnkpik nsvttkqwms alpdttnlaa
       61 lsipgthdtm syngditwtl tkplaqtqtm slyqqleagi ryidirakdn lniyhgpifl
      121 naslsgvlet itqflkknpk etiimrlkde qnsndsfdyr iqpliniykd yfyttprtdt
      181 snkiptlkdv rgkilllsen htkkplvins rkfgmqfgap nqviqddyng psvktkfkei
      241 vqtayqaska dnklflnhis atsltftprq yaaalnnkve qfvlnltsek vrglgilimd
      301 fpekqtikni iknnkfn