peroxide-responsive transcriptional repressor PerR [Listeria

LOCUS       WP_003733104             148 aa            linear   BCT 11-APR-2024
            monocytogenes].
ACCESSION   WP_003733104
VERSION     WP_003733104.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 148)
  AUTHORS   Ji,C.J., Yang,Y.M., Kim,J.H., Ryu,S.H., Youn,H. and Lee,J.W.
  TITLE     The roles of two O-donor ligands in the Fe(2+)-binding and
            H2O2-sensing by the Fe(2+)-dependent H2O2 sensor PerR
  JOURNAL   Biochem. Biophys. Res. Commun. 501 (2), 458-464 (2018)
   PUBMED   29738773
REFERENCE   2  (residues 1 to 148)
  AUTHORS   Ji,C.J., Kim,J.H., Won,Y.B., Lee,Y.E., Choi,T.W., Ju,S.Y., Youn,H.,
            Helmann,J.D. and Lee,J.W.
  TITLE     Staphylococcus aureus PerR Is a Hypersensitive Hydrogen Peroxide
            Sensor using Iron-mediated Histidine Oxidation
  JOURNAL   J. Biol. Chem. 290 (33), 20374-20386 (2015)
   PUBMED   26134568
REFERENCE   3  (residues 1 to 148)
  AUTHORS   Makthal,N., Rastegari,S., Sanson,M., Ma,Z., Olsen,R.J.,
            Helmann,J.D., Musser,J.M. and Kumaraswami,M.
  TITLE     Crystal structure of peroxide stress regulator from Streptococcus
            pyogenes provides functional insights into the mechanism of
            oxidative stress sensing
  JOURNAL   J. Biol. Chem. 288 (25), 18311-18324 (2013)
   PUBMED   23645680
REFERENCE   4  (residues 1 to 148)
  AUTHORS   Kim,M., Hwang,S., Ryu,S. and Jeon,B.
  TITLE     Regulation of perR expression by iron and PerR in Campylobacter
            jejuni
  JOURNAL   J. Bacteriol. 193 (22), 6171-6178 (2011)
   PUBMED   21908670
REFERENCE   5  (residues 1 to 148)
  AUTHORS   Maalej,S., Dammak,I. and Dukan,S.
  TITLE     The impairment of superoxide dismutase coordinates the derepression
            of the PerR regulon in the response of Staphylococcus aureus to
            HOCl stress
  JOURNAL   Microbiology (Reading, Engl.) 152 (Pt 3), 855-861 (2006)
   PUBMED   16514164
REFERENCE   6  (residues 1 to 148)
  AUTHORS   Horsburgh,M.J., Wharton,S.J., Cox,A.G., Ingham,E., Peacock,S. and
            Foster,S.J.
  TITLE     MntR modulates expression of the PerR regulon and superoxide
            resistance in Staphylococcus aureus through control of manganese
            uptake
  JOURNAL   Mol. Microbiol. 44 (5), 1269-1286 (2002)
   PUBMED   12028379
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007049
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..148
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..148
                     /gene="perR"
     Protein         1..148
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /calculated_mol_wt=16499
     Region          6..143
                     /region_name="Fur"
                     /note="Fe2+ or Zn2+ uptake regulation protein Fur/Zur
                     [Inorganic ion transport and metabolism]; COG0735"
                     /db_xref="CDD:440498"
ORIGIN      
        1 mavsnatlke avdvlkktgv ritpqrhail eflinshthp taddiyrale gnfpnmsvat
       61 vynnlrvfrd aglikelsyg dassrfdfst snhyhaicnv cgkivdfhyp gldevehfaa
      121 hmtgyeidnh rlevygicpa ckekqsnn