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tRNA pseudouridine(38-40) synthase TruA [Listeria monocytogenes].


LOCUS       WP_003733032             248 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_003733032
VERSION     WP_003733032.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 248)
  AUTHORS   Hur,S. and Stroud,R.M.
  TITLE     How U38, 39, and 40 of many tRNAs become the targets for
            pseudouridylation by TruA
  JOURNAL   Mol Cell 26 (2), 189-203 (2007)
   PUBMED   17466622
REFERENCE   2  (residues 1 to 248)
  AUTHORS   Dong,X., Bessho,Y., Shibata,R., Nishimoto,M., Shirouzu,M.,
            Kuramitsu,S. and Yokoyama,S.
  TITLE     Crystal structure of tRNA pseudouridine synthase TruA from Thermus
            thermophilus HB8
  JOURNAL   RNA Biol 3 (3), 115-122 (2006)
   PUBMED   17114947
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00071.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..248
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..248
                     /gene="truA"
     Protein         1..248
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /EC_number="5.4.99.12"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /calculated_mol_wt=28268
     Region          1..248
                     /region_name="TruA"
                     /note="tRNA U38,U39,U40 pseudouridine synthase TruA
                     [Translation, ribosomal structure and biogenesis];
                     COG0101"
                     /db_xref="CDD:439871"
ORIGIN      
        1 mtrykaiisy dgsgfygyqv qpntrtvqae iekaltkmhk gktvrvtasg rtdtgvhakg
       61 qvihfdseld itaekfqkal qvmtpfdisf ltveevpddf harfgtvgke yryvvkrtki
      121 fdpfsrnfal hypyeldisk mklaskrlig ehdftsfcsa rterdskvrt lysidfyeed
      181 detlviafqg ngflynmvri ltgtlldagq grispddise allardrqkl isktappqgl
      241 ylwrvdye