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MULTISPECIES: cysteine metabolism transcriptional regulator CymR


LOCUS       WP_003732594             140 aa            linear   BCT 04-AUG-2024
            [Listeria].
ACCESSION   WP_003732594
VERSION     WP_003732594.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 140)
  AUTHORS   Ji,Q., Zhang,L., Sun,F., Deng,X., Liang,H., Bae,T. and He,C.
  TITLE     Staphylococcus aureus CymR is a new thiol-based oxidation-sensing
            regulator of stress resistance and oxidative response
  JOURNAL   J Biol Chem 287 (25), 21102-21109 (2012)
   PUBMED   22553203
REFERENCE   2  (residues 1 to 140)
  AUTHORS   Soutourina,O., Dubrac,S., Poupel,O., Msadek,T. and
            Martin-Verstraete,I.
  TITLE     The pleiotropic CymR regulator of Staphylococcus aureus plays an
            important role in virulence and stress response
  JOURNAL   PLoS Pathog 6 (5), e1000894 (2010)
   PUBMED   20485570
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 140)
  AUTHORS   Soutourina,O., Poupel,O., Coppee,J.Y., Danchin,A., Msadek,T. and
            Martin-Verstraete,I.
  TITLE     CymR, the master regulator of cysteine metabolism in Staphylococcus
            aureus, controls host sulphur source utilization and plays a role
            in biofilm formation
  JOURNAL   Mol Microbiol 73 (2), 194-211 (2009)
   PUBMED   19508281
REFERENCE   4  (residues 1 to 140)
  AUTHORS   Tanous,C., Soutourina,O., Raynal,B., Hullo,M.F., Mervelet,P.,
            Gilles,A.M., Noirot,P., Danchin,A., England,P. and
            Martin-Verstraete,I.
  TITLE     The CymR regulator in complex with the enzyme CysK controls
            cysteine metabolism in Bacillus subtilis
  JOURNAL   J Biol Chem 283 (51), 35551-35560 (2008)
   PUBMED   18974048
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047409.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..140
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     gene            1..140
                     /gene="cymR"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
     Protein         1..140
                     /product="cysteine metabolism transcriptional regulator
                     CymR"
                     /calculated_mol_wt=15453
     Region          3..126
                     /region_name="Rrf2"
                     /note="Iron-dependent Transcriptional regulator;
                     pfam02082"
                     /db_xref="CDD:396591"
ORIGIN      
        1 mkittkgryg ltitlelakr igdgpislrs iaqdknlseh yleqligplr nagivksirg
       61 ahggyvlngd pekitagdii rtlegpivlv esmedeeaaq relwtrmrna vrdvldqttl
      121 adllkhstds eltdgymfyi