Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MetQ/NlpA family ABC transporter substrate-binding protein


LOCUS       WP_003732466             276 aa            linear   BCT 31-DEC-2024
            [Listeria monocytogenes].
ACCESSION   WP_003732466
VERSION     WP_003732466.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 276)
  AUTHORS   Maqbool,A., Horler,R.S., Muller,A., Wilkinson,A.J., Wilson,K.S. and
            Thomas,G.H.
  TITLE     The substrate-binding protein in bacterial ABC transporters:
            dissecting roles in the evolution of substrate specificity
  JOURNAL   Biochem Soc Trans 43 (5), 1011-1017 (2015)
   PUBMED   26517916
REFERENCE   2  (residues 1 to 276)
  AUTHORS   Wilkens,S.
  TITLE     Structure and mechanism of ABC transporters
  JOURNAL   F1000Prime Rep 7, 14 (2015)
   PUBMED   25750732
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 276)
  AUTHORS   ter Beek,J., Guskov,A. and Slotboom,D.J.
  TITLE     Structural diversity of ABC transporters
  JOURNAL   J Gen Physiol 143 (4), 419-435 (2014)
   PUBMED   24638992
REFERENCE   4  (residues 1 to 276)
  AUTHORS   Dawson,R.J., Hollenstein,K. and Locher,K.P.
  TITLE     Uptake or extrusion: crystal structures of full ABC transporters
            suggest a common mechanism
  JOURNAL   Mol Microbiol 65 (2), 250-257 (2007)
   PUBMED   17578454
REFERENCE   5  (residues 1 to 276)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10003704
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..276
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /calculated_mol_wt=30540
     Region          1..274
                     /region_name="NlpA"
                     /note="ABC-type metal ion transport system, periplasmic
                     component/surface antigen [Inorganic ion transport and
                     metabolism]; COG1464"
                     /db_xref="CDD:441073"
ORIGIN      
        1 mkkvlglift lslvlvltac ggssdkasss kddkqlvvga sntphaqile qakpilkdkg
       61 idlkivkytd yvmpnkalee gdldanyfqh kpyleleeke kgykfadvga ihiepmgiys
      121 kkvkdikdlk dgaqvllsns ksdwprvigi fvdnglltlk dgvkpqdatf ddikdnpknl
      181 kfkydfdpay lmtaynneeg dvvainsnfv vdqglnpskd aiaieskdsp yanivvttek
      241 kkddknitel vkvlhskeiq dyitkewdga vvpvdk