MULTISPECIES: THUMP domain-containing class I SAM-dependent RNA

LOCUS       WP_003732062             382 aa            linear   BCT 20-JAN-2025
            methyltransferase [Listeria].
ACCESSION   WP_003732062
VERSION     WP_003732062.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 382)
  AUTHORS   Schubert,H.L., Blumenthal,R.M. and Cheng,X.
  TITLE     Many paths to methyltransfer: a chronicle of convergence
  JOURNAL   Trends Biochem Sci 28 (6), 329-335 (2003)
   PUBMED   12826405
REFERENCE   2  (residues 1 to 382)
  AUTHORS   Martin,J.L. and McMillan,F.M.
  TITLE     SAM (dependent) I AM: the S-adenosylmethionine-dependent
            methyltransferase fold
  JOURNAL   Curr Opin Struct Biol 12 (6), 783-793 (2002)
   PUBMED   12504684
  REMARK    Erratum:[Curr Opin Struct Biol. 2003 Feb;13(1):142]
REFERENCE   3  (residues 1 to 382)
  AUTHORS   Aravind,L. and Koonin,E.V.
  TITLE     THUMP--a predicted RNA-binding domain shared by 4-thiouridine,
            pseudouridine synthases and RNA methylases
  JOURNAL   Trends Biochem Sci 26 (4), 215-217 (2001)
   PUBMED   11295541
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11414754
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     Protein         1..382
                     /product="THUMP domain-containing class I SAM-dependent
                     RNA methyltransferase"
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /calculated_mol_wt=42935
     Region          4..370
                     /region_name="RlmL"
                     /note="23S rRNA G2445 N2-methylase RlmL [Translation,
                     ribosomal structure and biogenesis]; COG0116"
                     /db_xref="CDD:439886"
ORIGIN      
        1 mktfqlvata asgleaivgk evarlgydpk vengkvyfeg dlsaiaranl wlrvadrvki
       61 vvgvfkattf delfektkal pwedylplda qfpvagksvk stlysvpdcq aivkkaivnr
      121 vsekyrrsgr lmetgalfkl evsilkdevt ltidtsgagl hkrgyrlaqg sapiketmaa
      181 alvlltswhp drpfydpvcg sgtipieaal igqniapgfn refvsetwdw mpkqiwadar
      241 qeaedlanyd qplniiggdi darlieiakq naveaglgdl itfrqlqvad fqtedeygvv
      301 vanppygerl edeeavrqly remgivykrm ptwsvyvlts yelfeevygk katkkrklyn
      361 gylrtdlyqy wgprkprpkk ed