substrate-binding domain-containing protein [Listeria

LOCUS       WP_003732008             336 aa            linear   BCT 02-MAR-2025
            monocytogenes].
ACCESSION   WP_003732008
VERSION     WP_003732008.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 336)
  AUTHORS   Swint-Kruse,L. and Matthews,K.S.
  TITLE     Allostery in the LacI/GalR family: variations on a theme
  JOURNAL   Curr Opin Microbiol 12 (2), 129-137 (2009)
   PUBMED   19269243
REFERENCE   2  (residues 1 to 336)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF024770.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF13377.12
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..336
                     /product="substrate-binding domain-containing protein"
                     /calculated_mol_wt=37882
     Region          3..73
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(6,14..18,20..21,24,30..31,34,47,50,53..54,56)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            47..56
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          63..329
                     /region_name="PBP1_DegA_Like"
                     /note="ligand-binding domain of putative DNA transcription
                     regulators highly similar to that of the transcription
                     regulator DegA; cd19976"
                     /db_xref="CDD:380631"
     Site            order(63,77,81,84,93..98,112..113,116..117,225,251..252,
                     255,258..259,285)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:380631"
     Site            order(75..76,148,194,197,274,291)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:380631"
ORIGIN      
        1 maatireiae ktgvsittis qilngkgerf sdltrekvlk takemsykpn ffaknmivsh
       61 tntigmivpe vtdpffsqmv kgaedylnke gymimlcnss ndkeredlyv eellhravdg
      121 liiaspnill sgvikrmeek rspyilldrq rnprqegnia iddfkggyma tehlielght
      181 rigiiisdts fynvheryeg ylacmkdyql pvkdswivsg dqtmnggyia tqkllqenls
      241 aifatndlma mgtyraalek nlriphdlsv igfddielse ymtpplttir qpiygigeia
      301 aelllknlqn pteklenrll dislikrsst ksidnq