MULTISPECIES: translation elongation factor 4 [Listeria].

LOCUS       WP_003726525             608 aa            linear   BCT 22-MAR-2021
ACCESSION   WP_003726525
VERSION     WP_003726525.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 608)
  AUTHORS   Gibbs,M.R., Moon,K.M., Chen,M., Balakrishnan,R., Foster,L.J. and
            Fredrick,K.
  TITLE     Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis
            of the 30S subunit of the 70S ribosome
  JOURNAL   Proc Natl Acad Sci U S A 114 (5), 980-985 (2017)
   PUBMED   28096346
REFERENCE   2  (residues 1 to 608)
  AUTHORS   Song,G. and Qin,Y.
  TITLE     EF4 reveals the energy barrier for tRNA back-translocation in the
            peptidyl transferase center
  JOURNAL   RNA Biol 13 (10), 934-939 (2016)
   PUBMED   27472653
REFERENCE   3  (residues 1 to 608)
  AUTHORS   Kumar,V., Ero,R., Ahmed,T., Goh,K.J., Zhan,Y., Bhushan,S. and
            Gao,Y.G.
  TITLE     Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the
            Ribosome
  JOURNAL   J Biol Chem 291 (25), 12943-12950 (2016)
   PUBMED   27137929
REFERENCE   4  (residues 1 to 608)
  AUTHORS   Liu,H., Chen,C., Zhang,H., Kaur,J., Goldman,Y.E. and Cooperman,B.S.
  TITLE     The conserved protein EF4 (LepA) modulates the elongation cycle of
            protein synthesis
  JOURNAL   Proc Natl Acad Sci U S A 108 (39), 16223-16228 (2011)
   PUBMED   21930951
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01393.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     gene            1..608
                     /gene="lepA"
     Protein         1..608
                     /product="translation elongation factor 4"
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /calculated_mol_wt=67692
     Region          9..605
                     /region_name="LepA"
                     /note="Translation elongation factor EF-4, membrane-bound
                     GTPase [Translation, ribosomal structure and biogenesis];
                     COG0481"
                     /db_xref="CDD:440249"
ORIGIN      
        1 mnkeemnarq kkirnfsiia hidhgkstla drileqtgal thremknqll dsmdlererg
       61 itiklnavql kykakdgety ifhlidtpgh vdftyevsrs laacegailv vdaaqgieaq
      121 tlanvylald ndleilpvin kidlpaadpe rvreeiedvi gldasdavla saksgigied
      181 ileqivekvp epsgdvnkpl kalifdsvfd ayrgvianir imdgvvkagd rikmmsngke
      241 fevtevgvfs pkatprdell vgdvgyltaa iknvgdtrvg dtitlannpa eealdgyrkl
      301 npmvycglyp idsskyndlr daleklelnd salqfeaets qalgfgfrcg flgllhmeii
      361 qerierefni dlittapsvi yhvnltdgsn ivvdnpaemp epgviesvee pyvkatvmvp
      421 ndyvgavmel aqnkrgnfit meylddirvs ivyeiplsei vydffdqlks stkgyasfdy
      481 eligykaskl vkmdillnae kvdalsfivh rdfayergki iveklkelip rqqfevpiqa
      541 aiatkivsrs tikalrknvl akcyggdvsr krkllekqke gkkrmkqigs vevpqeafma
      601 ilkmdesk