MULTISPECIES: MFS transporter [Listeria].

LOCUS       WP_003725797             422 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003725797
VERSION     WP_003725797.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 422)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 422)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 422)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022776
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     Protein         1..422
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=45392
     Region          11..399
                     /region_name="MFS_SV2_like"
                     /note="Metazoan Synaptic vesicle glycoprotein 2 (SV2) and
                     related small molecule transporters of the Major
                     Facilitator Superfamily; cd17316"
                     /db_xref="CDD:340874"
     Site            order(21..22,25..26,29,63,113..114,116..118,121,141,
                     144..145,148,231,234..235,238..240,243,272,276,327..328,
                     332,336,352,355..356,359..360,363)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340874"
ORIGIN      
        1 magsstskkg tiavsltnyl dsgcivagas gltlwatqfg lssfavgllg avsanafgsa
       61 igaligghla dkygrkfiyt ynmlvymlgv tiimfamnfp mlligflvtg lsvgagvpas
      121 wtyisemadp sirarnigis qfawscgpai iftlgiivsp lgllgnrllf lsllivafva
      181 wqlqrklees kdweaeqvkm kesgnrlehp fktafssmvn vksvlflvgv ylfwnlvaga
      241 mgffmpfvye tvgglsntqa nllqavlwil taastyfgfa kfgdrvshrg lffvgalmav
      301 aswvvltfvg mswvglwtfv ilwgisagig aqafyalwst elfptkyrgg vqgvmfflvr
      361 gstgvwsivf pvilanlgft vagtimigll tvslligviw apktrgrsld ditkerygnt
      421 id