Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: signal peptidase II [Listeria].


LOCUS       WP_003724127             154 aa            linear   BCT 17-OCT-2022
ACCESSION   WP_003724127
VERSION     WP_003724127.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 154)
  AUTHORS   Vogeley,L., El Arnaout,T., Bailey,J., Stansfeld,P.J., Boland,C. and
            Caffrey,M.
  TITLE     Structural basis of lipoprotein signal peptidase II action and
            inhibition by the antibiotic globomycin
  JOURNAL   Science 351 (6275), 876-880 (2016)
   PUBMED   26912896
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00077.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..154
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     gene            1..154
                     /gene="lspA"
     Protein         1..154
                     /product="signal peptidase II"
                     /EC_number="3.4.23.36"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence
                     IEA]"
                     /calculated_mol_wt=17592
     Region          1..151
                     /region_name="LspA"
                     /note="Lipoprotein signal peptidase [Cell
                     wall/membrane/envelope biogenesis, Intracellular
                     trafficking, secretion, and vesicular transport]; COG0597"
                     /db_xref="CDD:440362"
ORIGIN      
        1 myyylitlav ialdqltkwi vvqnmeigqk ievipgflyw tsyrndgaaw sileghmwff
       61 ylitvvvigi iiyimqkyak gkrlfsisla filggaignf idrvlhqevv dfvqtvwgny
      121 yfpifnvada slsvgvvlml vyvfvddrkt kgik