GTP pyrophosphokinase [Listeria monocytogenes].

LOCUS       WP_003723980             212 aa            linear   BCT 18-FEB-2025
ACCESSION   WP_003723980
VERSION     WP_003723980.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 212)
  AUTHORS   Das,B. and Bhadra,R.K.
  TITLE     (p)ppGpp Metabolism and Antimicrobial Resistance in Bacterial
            Pathogens
  JOURNAL   Front Microbiol 11, 563944 (2020)
   PUBMED   33162948
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 212)
  AUTHORS   Ronneau,S. and Hallez,R.
  TITLE     Make and break the alarmone: regulation of (p)ppGpp
            synthetase/hydrolase enzymes in bacteria
  JOURNAL   FEMS Microbiol Rev 43 (4), 389-400 (2019)
   PUBMED   30980074
REFERENCE   3  (residues 1 to 212)
  AUTHORS   Steinchen,W., Schuhmacher,J.S., Altegoer,F., Fage,C.D.,
            Srinivasan,V., Linne,U., Marahiel,M.A. and Bange,G.
  TITLE     Catalytic mechanism and allosteric regulation of an oligomeric
            (p)ppGpp synthetase by an alarmone
  JOURNAL   Proc Natl Acad Sci U S A 112 (43), 13348-13353 (2015)
   PUBMED   26460002
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10789386
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..212
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..212
                     /product="GTP pyrophosphokinase"
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /calculated_mol_wt=24858
     Region          7..>211
                     /region_name="YjbM"
                     /note="ppGpp synthetase catalytic domain (RelA/SpoT-type
                     nucleotidyltranferase) [Nucleotide transport and
                     metabolism, Signal transduction mechanisms]; COG2357"
                     /db_xref="CDD:441924"
ORIGIN      
        1 meqpsvdelk nwrnvmllhr faleevntkl kilneefqfi hdynpmehlk srvkslesig
       61 aklekkkvdi tpenalkyvh diagiritcs fvsdifrihe mlagqsditi krvkdyvtnp
      121 kpngyrslhl lcevpvfltn rseimtveiq irtvamdfwa slehkiyyky qqeapvelvn
      181 elqdaariit hldekmknln dqidkykkek en