tryptophan synthase subunit alpha [Listeria monocytogenes].

LOCUS       WP_003723933             257 aa            linear   BCT 27-MAY-2021
ACCESSION   WP_003723933
VERSION     WP_003723933.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 257)
  AUTHORS   Dunn,M.F.
  TITLE     Allosteric regulation of substrate channeling and catalysis in the
            tryptophan synthase bienzyme complex
  JOURNAL   Arch Biochem Biophys 519 (2), 154-166 (2012)
   PUBMED   22310642
REFERENCE   2  (residues 1 to 257)
  AUTHORS   Hyde,C.C., Ahmed,S.A., Padlan,E.A., Miles,E.W. and Davies,D.R.
  TITLE     Three-dimensional structure of the tryptophan synthase alpha 2 beta
            2 multienzyme complex from Salmonella typhimurium
  JOURNAL   J Biol Chem 263 (33), 17857-17871 (1988)
   PUBMED   3053720
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00262.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..257
                     /gene="trpA"
     Protein         1..257
                     /product="tryptophan synthase subunit alpha"
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=27760
     Region          8..252
                     /region_name="trpA"
                     /note="tryptophan synthase subunit alpha; Provisional;
                     PRK13111"
                     /db_xref="CDD:237285"
     Site            order(47,58,62,170,178..179,207..208,228..229)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:240075"
     Site            order(47,58,97,178)
                     /site_type="active"
                     /db_xref="CDD:240075"
     Site            order(47,58,97)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:240075"
     Site            order(52..55,57,60,63..64,99,102,124..125,127,130,150,
                     152..154,157)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:240075"
ORIGIN      
        1 mtktltnkla ekehaavvty imggdggldn leeqllflek sgvsaieigi pfsdpvadgp
       61 iiqlaglral keqvsleail nklamskvqi pliimsyinp ifhlgipkfv elvqktpvkg
      121 liipdlpyeh qklitpelqg tdialiplvs ltspkerlee iakqaegfiy avtvngttgv
      181 rsefdahids hlaylksisp vpvlagfgvs siehvekfah vcdgviigsk vvqmlheekt
      241 aelgaflqka aevrikn