mevalonate kinase [Listeria monocytogenes].

LOCUS       WP_003723774             322 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_003723774
VERSION     WP_003723774.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 322)
  AUTHORS   Humbelin,M., Thomas,A., Lin,J., Li,J., Jore,J. and Berry,A.
  TITLE     Genetics of isoprenoid biosynthesis in Paracoccus
            zeaxanthinifaciens
  JOURNAL   Gene 297 (1-2), 129-139 (2002)
   PUBMED   12384294
REFERENCE   2  (residues 1 to 322)
  AUTHORS   Huang,K.X., Scott,A.I. and Bennett,G.N.
  TITLE     Overexpression, purification, and characterization of the
            thermostable mevalonate kinase from Methanococcus jannaschii
  JOURNAL   Protein Expr Purif 17 (1), 33-40 (1999)
   PUBMED   10497066
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00549.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..322
                     /gene="mvk"
     Protein         1..322
                     /product="mevalonate kinase"
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /calculated_mol_wt=34085
     Region          8..278
                     /region_name="ERG12"
                     /note="Mevalonate kinase [Lipid transport and metabolism];
                     COG1577"
                     /db_xref="CDD:441185"
ORIGIN      
        1 matgigtakm ilcgehavvy gepaisvpft qavvttnvet siktkfssaf fsgdlddmpd
       61 flagikalvv dvlneignge cvsihvvsgv pigrglgssa avatsiargl ykyfnqelds
      121 kkllaivnaa ekiahgnasg vdaitvvsek pvwyerdrkl eimhfpkkit fvvadtgvps
      181 etrdavkdvq vlykenqvei gkiihqlgdi sreikthleg dadtvkigaa mnkaqsylet
      241 ltvsdsslek likvarsnga dgakltgggr ggciiavakn qeiaeqitka lhnagaaqew
      301 iftigegsye sdshrthecg an