MFS transporter [Listeria monocytogenes].

LOCUS       WP_003723717             470 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003723717
VERSION     WP_003723717.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 470)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 470)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 470)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022956
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..470
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=50144
     Region          15..467
                     /region_name="MFS_MMR_MDR_like"
                     /note="Methylenomycin A resistance protein (also called
                     MMR peptide) and similar multidrug resistance (MDR)
                     transporters of the Major Facilitator Superfamily;
                     cd17321"
                     /db_xref="CDD:340879"
     Site            order(22..23,26..27,30,62,112..113,115..117,120,140,
                     143..144,147,279,282..283,286..288,291,319,323,378..379,
                     383,387,403,406..407,410..411,414)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340879"
ORIGIN      
        1 meqtnkrntl alisimlgaf islldttivn valpdittal hatsetiewv isgyalafgl
       61 vlilagrlgd kfgrkniyii gitlflimsv tagfadsens liisrviqgl aaglffpqin
      121 atimdmysgk slgkifgilg svigvgtaig pltgglliel fgatngwrav ffvnvpfvlv
      181 tlvlamlylp krtvstkkis fdlpgvgllt ialllllfpl isngandfkp vdyflmalsi
      241 plfiilykws vyqekkgnqp liapnllknn qfvsgmllsl vyfaaftsif fvlsltwqtg
      301 fnrsailsgl aispfalgsv laasnsyrli pllgrkllml gvtlvivglg tvsivfhlnd
      361 gafsawllfl plfiagigsg ltiaplnsft lstvtgidrg gasgmfntaq rigssfgiav
      421 vgsvffrtlg ntaatskasa fsdslqmsmy vnivllvvcf llvfrlpkni