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dihydrofolate reductase family protein [Listeria monocytogenes].


LOCUS       WP_003723621             174 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003723621
VERSION     WP_003723621.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 174)
  AUTHORS   Slansky,J.E. and Farnham,P.J.
  TITLE     Transcriptional regulation of the dihydrofolate reductase gene
  JOURNAL   Bioessays 18 (1), 55-62 (1996)
   PUBMED   8593164
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10000815
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..174
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..174
                     /product="dihydrofolate reductase family protein"
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=19503
     Region          6..168
                     /region_name="FolA"
                     /note="Dihydrofolate reductase [Coenzyme transport and
                     metabolism]; COG0262"
                     /db_xref="CDD:440032"
ORIGIN      
        1 msekqvalyi avsldgyiad engsvewles idsegdagye affdnvdtvv mgrttyqqif
       61 sltdtfpysk kdvyvfsntk agtkdeyadf vagtvdtwln nidgekiwlv ggaklvqqfl
      121 keraidrfvi tiapiilgkg iplfeedqeh aleleevtrf gqfaqltykn leen