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MULTISPECIES: 2-hydroxymuconate tautomerase [Listeria].


LOCUS       WP_003723612              61 aa            linear   BCT 13-MAY-2024
ACCESSION   WP_003723612
VERSION     WP_003723612.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 61)
  AUTHORS   Wang,S.C., Johnson,W.H. Jr., Czerwinski,R.M., Stamps,S.L. and
            Whitman,C.P.
  TITLE     Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate
            tautomerase homologue in Bacillus subtilis: mechanistic
            implications for the YwhB- and 4-oxalocrotonate
            tautomerase-catalyzed reactions
  JOURNAL   Biochemistry 46 (42), 11919-11929 (2007)
   PUBMED   17902707
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002571.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK02220
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..61
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     Protein         1..61
                     /product="2-hydroxymuconate tautomerase"
                     /EC_number="5.3.2.6"
                     /GO_function="GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=6730
     Region          1..60
                     /region_name="4Oxalocrotonate_Tautomerase"
                     /note="4-Oxalocrotonate Tautomerase: Catalyzes the
                     isomerization of unsaturated ketones. The structure is a
                     homohexamer that is arranged as a trimer of dimers. The
                     hexamer contains six active sites, each formed by residues
                     from three monomers, two from one...; cl00235"
                     /db_xref="CDD:444774"
     Site            order(2..3,38)
                     /site_type="active"
                     /note="active site 1 [active]"
                     /db_xref="CDD:238274"
     Site            order(2..8,20,23..24,27,31..32)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238274"
     Site            order(5,7,17..18,21..22,25,36..37,39..43,45..46,49..57)
                     /site_type="other"
                     /note="hexamer interface [polypeptide binding]"
                     /db_xref="CDD:238274"
     Site            order(7,51)
                     /site_type="active"
                     /note="active site 2 [active]"
                     /db_xref="CDD:238274"
ORIGIN      
        1 mpfvtiqfle grtddqkkal vsevtevvsk nlkapkenih vileemkktd ygvggvrksd
       61 i