YtnP family quorum-quenching lactonase [Listeria monocytogenes].

LOCUS       WP_003723579             283 aa            linear   BCT 13-JAN-2025
ACCESSION   WP_003723579
VERSION     WP_003723579.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 283)
  AUTHORS   Djokic,L., Stankovic,N., Galic,I., Moric,I., Radakovic,N.,
            Segan,S., Pavic,A. and Senerovic,L.
  TITLE     Novel Quorum Quenching YtnP Lactonase From Bacillus
            paralicheniformis Reduces Pseudomonas aeruginosa Virulence and
            Increases Antibiotic Efficacy in vivo
  JOURNAL   Front Microbiol 13, 906312 (2022)
   PUBMED   35722344
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 283)
  AUTHORS   Schneider,J., Yepes,A., Garcia-Betancur,J.C., Westedt,I.,
            Mielich,B. and Lopez,D.
  TITLE     Streptomycin-induced expression in Bacillus subtilis of YtnP, a
            lactonase-homologous protein that inhibits development and
            streptomycin production in Streptomyces griseus
  JOURNAL   Appl Environ Microbiol 78 (2), 599-603 (2012)
   PUBMED   22101040
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047919.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..283
                     /product="YtnP family quorum-quenching lactonase"
                     /EC_number="3.1.1.-"
                     /calculated_mol_wt=32661
     Region          9..258
                     /region_name="YtnP-like_MBL-fold"
                     /note="Bacillus subtilis YtnP and related proteins;
                     MBL-fold metallo hydrolase domain; cd07728"
                     /db_xref="CDD:293814"
     Site            order(111,113,115..116,192..193,213,258)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:293814"
ORIGIN      
        1 mdsiqigkik iywlrggyth fdggamfgvv pkplwekkyp vndknqlanv tdpmffqylg
       61 knylidsglg nrrltekqkr nygvteesfv ledlaqlsia pedidyvlmt hlhfdhvlgl
      121 tgiseegndy sifpnaeiwt seteweemqh pnirskatyw qenwlriegq ihtftkekef
      181 ndaikmthtg ghsnghsviw lesdgekaih madifptfah qnvlwvtayd dypmtsisak
      241 qaifkqtfga nywflsyhds rfravqiaen gdvkaelkie hrn