bifunctional folylpolyglutamate synthase/dihydrofolate synthase

LOCUS       WP_003723235             429 aa            linear   BCT 24-DEC-2024
            [Listeria monocytogenes].
ACCESSION   WP_003723235
VERSION     WP_003723235.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11416298
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..429
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /EC_number="6.3.2.-"
                     /GO_function="GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=47561
     Region          4..425
                     /region_name="FolC"
                     /note="Folylpolyglutamate synthase/Dihydropteroate
                     synthase [Coenzyme transport and metabolism]; COG0285"
                     /db_xref="CDD:440054"
ORIGIN      
        1 mtlnsyeeal dwihgtlrlg ikpglarmey mmeklnhpek ankwvhiagt ngkgstltfv
       61 rnaleeagyk agtftspyie vfnerisvng episdemivs lanrikpiae elektvygpp
      121 sefeiitamm flcfadyvsi digiievglg grldstnilv plvsvittig mdhmeflgdt
      181 ieqiasekag iikpgipvvs gaiqkeaqev iaeiatknks nvtqlnkafs mhnengnity
      241 ktiygeeisn lsiglfglhq lnnaavaikv lqylntfstf eidlaairkg lekafwpgrm
      301 ekiisnpfim ldgahnpegi ktfahsvqky pgpkkiivsi ladknyqeml amlksipnae
      361 iilttfdypr ammaeeviqi gknegislnp dwqqalnnly etetntkifi tgslyfisev
      421 rkyllasir