MULTISPECIES: 2-isopropylmalate synthase [Listeria].

LOCUS       WP_003723152             512 aa            linear   BCT 19-AUG-2020
ACCESSION   WP_003723152
VERSION     WP_003723152.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002088.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00915
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     Protein         1..512
                     /product="2-isopropylmalate synthase"
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=55965
     Region          1..495
                     /region_name="PRK00915"
                     /note="2-isopropylmalate synthase; Validated"
                     /db_xref="CDD:234864"
     Site            order(12..13,16,43,74,96,138,140,168,170,201,203)
                     /site_type="active"
                     /db_xref="CDD:163678"
     Site            order(12..13,43)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     Site            order(201,203)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:163678"
ORIGIN      
        1 mkkiqffdtt lrdgeqtpgv nfdvkekiqi alqleklgid vieagfpiss pgdfecvkai
       61 akaikhcsvt glarcvegdi draeealkda vspqihifla tsdvhmeykl kmsraevlas
      121 ikhhisyarq kfevvqfspe datrsdrafl ieavqtaida gatvinipdt vgytnptefg
      181 qlfqdlrrei kqfdditfas hchddlgmat analaaieng arrvegting igeragntal
      241 eevavalhir kdfyqaetni vlnqfknssd lisrlsgmpv prnkaviggn ayahesgihq
      301 dgvlknpdty eiitpalvgv dknslplgkl sgkhafntrm eemgytlteq eqkdafkrfk
      361 qladakkevt eedlhalilg qssesaddfe lkhlqvqyvt ggvqgaivri eerdgalved
      421 aatgsgsiea iyntinrlmk qdieltdyri qaitagqdaq aevhvviknd kgaefhgigi
      481 dfdvltasak aylqasgksk taskqadfee vk