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pantoate--beta-alanine ligase [Listeria monocytogenes].


LOCUS       WP_003723011             285 aa            linear   BCT 11-APR-2024
ACCESSION   WP_003723011
VERSION     WP_003723011.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 285)
  AUTHORS   Chakrabarti,K.S., Thakur,K.G., Gopal,B. and Sarma,S.P.
  TITLE     X-ray crystallographic and NMR studies of pantothenate synthetase
            provide insights into the mechanism of homotropic inhibition by
            pantoate
  JOURNAL   FEBS J 277 (3), 697-712 (2010)
   PUBMED   20059543
REFERENCE   2  (residues 1 to 285)
  AUTHORS   Zheng,R. and Blanchard,J.S.
  TITLE     Steady-state and pre-steady-state kinetic analysis of Mycobacterium
            tuberculosis pantothenate synthetase
  JOURNAL   Biochemistry 40 (43), 12904-12912 (2001)
   PUBMED   11669627
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00018.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..285
                     /gene="panC"
     Protein         1..285
                     /product="pantoate--beta-alanine ligase"
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=31998
     Region          1..281
                     /region_name="PanC"
                     /note="Panthothenate synthetase [Coenzyme transport and
                     metabolism]; COG0414"
                     /db_xref="CDD:440183"
ORIGIN      
        1 mliirnkqel kevilkqkqa nktigfvptm gflheghmtl vsharkesdf vvmsvfvnpt
       61 qfgpnedfda yprdeahdak laeeggvdil fvptveeiyp telstklhvd krvsvldgad
      121 reghfdgvvt vltklfhlvs pdnayfgqkd aqqvavvsgl vedyffpvnl riiatvread
      181 glakssrnvy ltekerkeap vihealqlgr kliesgetnq akivqmmtek ineqtsheli
      241 aylaiysype ftpvtdwskg iiiaaavkys karlidneli nvkrr