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ComEC/Rec2 family competence protein [Listeria monocytogenes].


LOCUS       WP_003722895             280 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_003722895
VERSION     WP_003722895.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 280)
  AUTHORS   Bebrone,C.
  TITLE     Metallo-beta-lactamases (classification, activity, genetic
            organization, structure, zinc coordination) and their superfamily
  JOURNAL   Biochem Pharmacol 74 (12), 1686-1701 (2007)
   PUBMED   17597585
REFERENCE   2  (residues 1 to 280)
  AUTHORS   Daiyasu,H., Osaka,K., Ishino,Y. and Toh,H.
  TITLE     Expansion of the zinc metallo-hydrolase family of the
            beta-lactamase fold
  JOURNAL   FEBS Lett 503 (1), 1-6 (2001)
   PUBMED   11513844
REFERENCE   3  (residues 1 to 280)
  AUTHORS   Aravind,L.
  TITLE     An evolutionary classification of the metallo-beta-lactamase fold
            proteins
  JOURNAL   In Silico Biol 1 (2), 69-91 (1999)
   PUBMED   11471246
REFERENCE   4  (residues 1 to 280)
  AUTHORS   Solomon,J.M. and Grossman,A.D.
  TITLE     Who's competent and when: regulation of natural genetic competence
            in bacteria
  JOURNAL   Trends Genet 12 (4), 150-155 (1996)
   PUBMED   8901420
REFERENCE   5  (residues 1 to 280)
  AUTHORS   Hahn,J., Inamine,G., Kozlov,Y. and Dubnau,D.
  TITLE     Characterization of comE, a late competence operon of Bacillus
            subtilis required for the binding and uptake of transforming DNA
  JOURNAL   Mol Microbiol 10 (1), 99-111 (1993)
   PUBMED   7968523
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457082
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..280
                     /product="ComEC/Rec2 family competence protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /calculated_mol_wt=29896
     Region          34..278
                     /region_name="ComEC"
                     /note="DNA uptake channel protein ComEC C-terminal domain,
                     metallo-beta-lactamase superfamily [Intracellular
                     trafficking, secretion, and vesicular transport]; COG2333"
                     /db_xref="CDD:441904"
ORIGIN      
        1 mkkgilnvll vfaliaglsv pssmqveaaa ptikvhfidv gqgdaiyika psgedilida
       61 gnkgkgktvv nylkklkvkd ieimiashsd adnigglpev mnnikvknly apkstnttaa
      121 yknfvntakk kkltiktaka gvklpvkgvn aqfvgpvkty gktdrnnwsa vlhvaykknt
      181 flftgdaqtk aendmikakk tlradvlkvs tqgskaatsk afvnvvkpky aiisvgkngy
      241 ghptsqtvnt lkkakakvyr tdrnktvvvt gngssysigk