AI-2E family transporter [Listeria monocytogenes].

LOCUS       WP_003722770             348 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003722770
VERSION     WP_003722770.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 348)
  AUTHORS   Khera,R., Mehdipour,A.R., Bolla,J.R., Kahnt,J., Welsch,S.,
            Ermler,U., Muenke,C., Robinson,C.V., Hummer,G., Xie,H. and
            Michel,H.
  TITLE     Cryo-EM structures of pentameric autoinducer-2 exporter from
            Escherichia coli reveal its transport mechanism
  JOURNAL   EMBO J 41 (18), e109990 (2022)
   PUBMED   35698912
REFERENCE   2  (residues 1 to 348)
  AUTHORS   Rettner,R.E. and Saier,M.H. Jr.
  TITLE     The autoinducer-2 exporter superfamily
  JOURNAL   J Mol Microbiol Biotechnol 18 (4), 195-205 (2010)
   PUBMED   20559013
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001851
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..348
                     /product="AI-2E family transporter"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=39116
     Region          30..328
                     /region_name="PerM"
                     /note="Predicted PurR-regulated permease PerM [General
                     function prediction only]; COG0628"
                     /db_xref="CDD:440393"
ORIGIN      
        1 mnwleklken dtarrvlvfv llgvvlyllr smidlilltf ifaflvtrle nvilkrvrvp
       61 rklivivlys lvavflyvai vhflpilinq isqlvdslvk lynnpsdnti vkwivgflke
      121 sniqkylqag vdfiiaslsg igsvglsffl alilslffsl ekervtsftg qfmtskvgfi
      181 fkeaaffgkk fvstfgvvle aqlmialvnt fittialylm dfpqllslsi mvfvlglipv
      241 agviiscipl vliaysvggf qdvvyilitv vivhaietyi lnpklmsskt nlpvfytfii
      301 lifsetffgv wglivgipvf vflldilevr naedlkkrtl fgrkkkvd