cholesterol-dependent cytolysin listeriolysin O [Listeria

LOCUS       WP_003722731             529 aa            linear   BCT 11-APR-2024
            monocytogenes].
ACCESSION   WP_003722731
VERSION     WP_003722731.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 529)
  AUTHORS   Mengaud,J., Chenevert,J., Geoffroy,C., Gaillard,J.L. and Cossart,P.
  TITLE     Identification of the structural gene encoding the SH-activated
            hemolysin of Listeria monocytogenes: listeriolysin O is homologous
            to streptolysin O and pneumolysin
  JOURNAL   Infect. Immun. 55 (12), 3225-3227 (1987)
   PUBMED   2824384
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR001027
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..529
                     /gene="hly"
     Protein         1..529
                     /product="cholesterol-dependent cytolysin listeriolysin O"
                     /calculated_mol_wt=58557
     Region          60..414
                     /region_name="Thiol_cytolysin"
                     /note="Thiol-activated cytolysin; pfam01289"
                     /db_xref="CDD:426182"
     Region          418..519
                     /region_name="Thiol_cytolys_C"
                     /note="Thiol-activated cytolysin beta sandwich domain;
                     pfam17440"
                     /db_xref="CDD:435915"
ORIGIN      
        1 mkkimlvfit lilvslpiaq qteakdasaf nkensissma ppasppaspk tpiekkhade
       61 idkyiqgldy nknnvlvyhg davtnvpprk gykdgneyiv vekkkksinq nnadiqvvna
      121 issltypgal vkanselven qpdvlpvkrd sltlsidlpg mtnqdnkivv knatksnvnn
      181 avntlverwn ekyaqaypnv sakidyddem aysesqliak fgtafkavnn slnvnfgais
      241 egkmqeevis fkqiyynvnv neptrpsrff gkavtkeqlq algvnaenpp ayissvaygr
      301 qvylklstns hstkvkaafd aavsgksvsg dveltniikn ssfkaviygg sakdevqiid
      361 gnlgdlrdil kkgatfnret pgvpiayttn flkdnelavi knnseyiett skaytdgkin
      421 idhsggyvaq fniswdevny dpegneivqh knwsennksk lahftssiyl pgnarninvy
      481 akectglawe wwrtviddrn lplvknrnis iwgttlypky snkvdnpie