MULTISPECIES: listeriolysin O transcriptional regulator PrfA

LOCUS       WP_003722729             237 aa            linear   BCT 06-MAR-2023
            [Listeria].
ACCESSION   WP_003722729
VERSION     WP_003722729.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 237)
  AUTHORS   Ripio,M.T., Dominguez-Bernal,G., Lara,M., Suarez,M. and
            Vazquez-Boland,J.A.
  TITLE     A Gly145Ser substitution in the transcriptional activator PrfA
            causes constitutive overexpression of virulence factors in Listeria
            monocytogenes
  JOURNAL   J. Bacteriol. 179 (5), 1533-1540 (1997)
   PUBMED   9045810
REFERENCE   2  (residues 1 to 237)
  AUTHORS   Mengaud,J., Dramsi,S., Gouin,E., Vazquez-Boland,J.A., Milon,G. and
            Cossart,P.
  TITLE     Pleiotropic control of Listeria monocytogenes virulence factors by
            a gene that is autoregulated
  JOURNAL   Mol. Microbiol. 5 (9), 2273-2283 (1991)
   PUBMED   1662763
REFERENCE   3  (residues 1 to 237)
  AUTHORS   Leimeister-Wachter,M., Haffner,C., Domann,E., Goebel,W. and
            Chakraborty,T.
  TITLE     Identification of a gene that positively regulates expression of
            listeriolysin, the major virulence factor of listeria monocytogenes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87 (21), 8336-8340 (1990)
   PUBMED   2122460
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR001116
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..237
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     gene            1..237
                     /gene="prfA"
     Protein         1..237
                     /product="listeriolysin O transcriptional regulator PrfA"
                     /calculated_mol_wt=27170
     Region          18..218
                     /region_name="Crp"
                     /note="cAMP-binding domain of CRP or a regulatory subunit
                     of cAMP-dependent protein kinases [Signal transduction
                     mechanisms]; COG0664"
                     /db_xref="CDD:440428"
ORIGIN      
        1 mnaqaeefkk yletngikpk qfhkkelifn qwdpqeycif lydgitklts isengtimnl
       61 qyykgafvim sgfidtetsv gyynlevise qatayvikin elkellsknl thffyvfqtl
      121 qkqvsyslak fndfsingkl gsicgqllil tyvygketpd gikitldnlt mqelgyssgi
      181 ahssavsrii sklkqekviv yknscfyvqn ldylkryapk ldewfylacp atwgkln