MULTISPECIES: thioredoxin-disulfide reductase [Listeria].

LOCUS       WP_003722610             319 aa            linear   BCT 08-JUL-2024
ACCESSION   WP_003722610
VERSION     WP_003722610.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 319)
  AUTHORS   Lin,K., O'Brien,K.M., Trujillo,C., Wang,R., Wallach,J.B.,
            Schnappinger,D. and Ehrt,S.
  TITLE     Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for
            Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant
            Defense
  JOURNAL   PLoS Pathog 12 (6), e1005675 (2016)
   PUBMED   27249779
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 319)
  AUTHORS   Kashima,Y. and Ishikawa,K.
  TITLE     A hyperthermostable novel protein-disulfide oxidoreductase is
            reduced by thioredoxin reductase from hyperthermophilic archaeon
            Pyrococcus horikoshii
  JOURNAL   Arch Biochem Biophys 418 (2), 179-185 (2003)
   PUBMED   14522589
REFERENCE   3  (residues 1 to 319)
  AUTHORS   Prongay,A.J., Engelke,D.R. and Williams,C.H. Jr.
  TITLE     Characterization of two active site mutations of thioredoxin
            reductase from Escherichia coli
  JOURNAL   J Biol Chem 264 (5), 2656-2664 (1989)
   PUBMED   2644268
  REMARK    Erratum:[J Biol Chem 1989 Jul 15;264(20):12113]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01292.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     gene            1..319
                     /gene="trxB"
     Protein         1..319
                     /product="thioredoxin-disulfide reductase"
                     /EC_number="1.8.1.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /calculated_mol_wt=34043
     Region          9..306
                     /region_name="TRX_reduct"
                     /note="thioredoxin-disulfide reductase; TIGR01292"
                     /db_xref="CDD:273540"
ORIGIN      
        1 maseekiydv iiigagpagm taalytsrad ldtlmiergv pggqmvntae venypgfdsi
       61 lgpdlsdkml sgakqfgaey aygdikevvd gkefktvtag sktykaraii iatgaehrkl
      121 gaageeelsg rgvsycavcd gaffknreli vvgggdsave egtyltryad kvtivhrrdk
      181 lraqqilqdr afkdekvdfi wnstveeivg dgkkvtgakl vstvdgsesi mpvdgvfiyv
      241 glvpltkafl nlgitddegy ivtdeemrtn lpgifaagdv rakslrqivt atgdgglagq
      301 naqkyveelk esleaeaak