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efflux pump transcriptional regulator FepR [Listeria


LOCUS       WP_003722345             196 aa            linear   BCT 11-APR-2024
            monocytogenes].
ACCESSION   WP_003722345
VERSION     WP_003722345.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 196)
  AUTHORS   Bolten,S., Harrand,A.S., Skeens,J. and Wiedmann,M.
  TITLE     Nonsynonymous Mutations in fepR Are Associated with Adaptation of
            Listeria monocytogenes and Other Listeria spp. to Low
            Concentrations of Benzalkonium Chloride but Do Not Increase
            Survival of L. monocytogenes and Other Listeria spp. after Exposure
            to Benzalkonium Chloride Concentrations Recommended for Use in Food
            Processing Environments
  JOURNAL   Appl Environ Microbiol 88 (11), e0048622 (2022)
   PUBMED   35587542
REFERENCE   2  (residues 1 to 196)
  AUTHORS   Douarre,P.E., Sevellec,Y., Le Grandois,P., Soumet,C., Bridier,A.
            and Roussel,S.
  TITLE     FepR as a Central Genetic Target in the Adaptation to Quaternary
            Ammonium Compounds and Cross-Resistance to Ciprofloxacin in
            Listeria monocytogenes
  JOURNAL   Front Microbiol 13, 864576 (2022)
   PUBMED   35663878
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 196)
  AUTHORS   Guerin,F., Galimand,M., Tuambilangana,F., Courvalin,P. and
            Cattoir,V.
  TITLE     Overexpression of the novel MATE fluoroquinolone efflux pump FepA
            in Listeria monocytogenes is driven by inactivation of its local
            repressor FepR
  JOURNAL   PLoS One 9 (9), e106340 (2014)
   PUBMED   25188450
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR015270
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..196
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..196
                     /gene="fepR"
     Protein         1..196
                     /product="efflux pump transcriptional regulator FepR"
                     /calculated_mol_wt=22710
     Region          2..161
                     /region_name="AcrR"
                     /note="DNA-binding protein, AcrR family, includes nucleoid
                     occlusion protein SlmA [Transcription]; COG1309"
                     /db_xref="CDD:440920"
ORIGIN      
        1 mrkeeikqaa ltlfanngfe gtsladiagv vglkkqsiys hfkdkddlfl simkdakste
       61 idyyraklrd sdlsrpdlvl ssllfgvkel ydtdeayqfw lrygfyppkh lyevvqadit
      121 envlqmehef tdlfsnwmeq klipmqdvet mkeaymgild avivdivyvn dpertekkit
      181 alwqifwrgi tlkaln