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hemin/hemoglobin-binding protein Hbp2 [Listeria monocytogenes].


LOCUS       WP_003722309             569 aa            linear   BCT 11-MAY-2020
ACCESSION   WP_003722309
VERSION     WP_003722309.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 569)
  AUTHORS   Malmirchegini,G.R., Sjodt,M., Shnitkind,S., Sawaya,M.R.,
            Rosinski,J., Newton,S.M., Klebba,P.E. and Clubb,R.T.
  TITLE     Novel mechanism of hemin capture by Hbp2, the hemoglobin-binding
            hemophore from Listeria monocytogenes
  JOURNAL   J. Biol. Chem. 289 (50), 34886-34899 (2014)
   PUBMED   25315777
REFERENCE   2  (residues 1 to 569)
  AUTHORS   Xiao,Q., Jiang,X., Moore,K.J., Shao,Y., Pi,H., Dubail,I.,
            Charbit,A., Newton,S.M. and Klebba,P.E.
  TITLE     Sortase independent and dependent systems for acquisition of haem
            and haemoglobin in Listeria monocytogenes
  JOURNAL   Mol. Microbiol. 80 (6), 1581-1597 (2011)
   PUBMED   21545655
REFERENCE   3  (residues 1 to 569)
  AUTHORS   Newton,S.M., Klebba,P.E., Raynaud,C., Shao,Y., Jiang,X., Dubail,I.,
            Archer,C., Frehel,C. and Charbit,A.
  TITLE     The svpA-srtB locus of Listeria monocytogenes: fur-mediated iron
            regulation and effect on virulence
  JOURNAL   Mol. Microbiol. 55 (3), 927-940 (2005)
   PUBMED   15661014
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011926
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..569
                     /gene="hbp2"
     Protein         1..569
                     /product="hemin/hemoglobin-binding protein Hbp2"
                     /calculated_mol_wt=63250
     Region          33..166
                     /region_name="NEAT"
                     /note="Iron Transport-associated domain; pfam05031"
                     /db_xref="CDD:428269"
     Site            order(47,59..60,63,88,148,150,155,159,161)
                     /site_type="other"
                     /note="heme-binding site [chemical binding]"
                     /db_xref="CDD:132993"
     Region          154..>385
                     /region_name="NEAT"
                     /note="Heme-binding NEAT domain [Inorganic ion transport
                     and metabolism]; COG5386"
                     /db_xref="CDD:444149"
     Region          362..483
                     /region_name="NEAT"
                     /note="NEAr Transporter domain; smart00725"
                     /db_xref="CDD:214790"
     Site            order(373,381..382,385,410,456,461,466,470,472)
                     /site_type="other"
                     /note="heme-binding site [chemical binding]"
                     /db_xref="CDD:132993"
     Region          536..564
                     /region_name="srtB_target"
                     /note="sortase B cell surface sorting signal; TIGR03063"
                     /db_xref="CDD:213766"
ORIGIN      
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       61 dkyidhtati kvengqpymy ltitnstwwq tmavskngtr pekpaqadvy qdryedvqtv
      121 stdaakdtrv ekfklssldd vifsymhikv daisydhwyq vdltidpstf kvisepavtt
      181 pvtlsdgiyt ipfvakkand dsnssmqnyf nnpawlkvkn gkkmvamtvn dnktvtalkt
      241 tlagtlqdvk vvsedkdant rivefevedl nqplaahvny eapfngsvyk gqadfryvfd
      301 takataassy pgsdetppvv npgetnppvt kpdpgttnpp vttppttpsk pavvdpknll
      361 nnhtysidfd vfkdgttets mmesyvmkpa likvennqpy vyltltnssw iktfqykvng
      421 vwkdmevvsg dinkntrtvk ypvkdgtant dvkthvlied mpgfsydhey tvqvklnaat
      481 ikditgkdvt lkepvkkdil ntgnvasnnn agpklakpdf ddtnsvqkta skteknaktn
      541 dsssmvwyit lfgasflyla yrlkrkrls