cyclic-di-AMP phosphodiesterase PgpH [Listeria monocytogenes].

LOCUS       WP_003721972             718 aa            linear   BCT 03-OCT-2019
ACCESSION   WP_003721972
VERSION     WP_003721972.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 718)
  AUTHORS   Gundlach,J., Mehne,F.M., Herzberg,C., Kampf,J., Valerius,O.,
            Kaever,V. and Stulke,J.
  TITLE     An Essential Poison: Synthesis and Degradation of Cyclic Di-AMP in
            Bacillus subtilis
  JOURNAL   J. Bacteriol. 197 (20), 3265-3274 (2015)
   PUBMED   26240071
REFERENCE   2  (residues 1 to 718)
  AUTHORS   Huynh,T.N., Luo,S., Pensinger,D., Sauer,J.D., Tong,L. and
            Woodward,J.J.
  TITLE     An HD-domain phosphodiesterase mediates cooperative hydrolysis of
            c-di-AMP to affect bacterial growth and virulence
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 112 (7), E747-E756 (2015)
   PUBMED   25583510
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR001114
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..718
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..718
                     /gene="pgpH"
     Protein         1..718
                     /product="cyclic-di-AMP phosphodiesterase PgpH"
                     /EC_number="3.1.4.59"
                     /calculated_mol_wt=80982
     Region          1..717
                     /region_name="PgpH"
                     /note="Cyclic di-AMP-specific phosphodiesterase PgpH, HD
                     superfamily [Signal transduction mechanisms]; COG1480"
                     /db_xref="CDD:441089"
ORIGIN      
        1 mklakkwrdw yiesgkkylf plllvcfavi ayflvcqmtk pesynvklfq vaektirspq
       61 tvedtektke ertkasdave dvyvynretg qnrvaliqsl fayvnevnae aqekdtknke
      121 kakkenkpap aptstedklk nlkdklssnv sekitsnisd evfttlieak skdfnvmedv
      181 vtteveksme nkirdenlns vkirarddie lsaipayykn vskalvsyai vpnevydeeq
      241 tdarrkeaaq svvpvkilqg qvivqegqiv dretyrqlkm lhlldqkmpv kqyagfaifi
      301 ialaailfly tkkqtqpkak kmqtmlifss vylvslfmlf iilfletqni aniaflfpaa
      361 fapmilkill nekyaflsvi fiavtslltf qndatsgiti fillsgatsv vmlrdysrrs
      421 aimlsgfmvg linmiyvlll llinnstllq vstlmalgya flggfgafil gvgviplfet
      481 ifgllttsrl velanpnhpl lkkilmkapg tyhhsmmvan laeacadkig ansllvrvgc
      541 fyhdigktlr ppyfvenqlq ginphdrltp eqsrdiilsh tkdgaeilke nhmpqpiidi
      601 alqhhgttll kyfyfkaket npdvkeadyr ysgpkpqtke iaiinisdsv eaavrsstep
      661 tmakiteiid giikdrfldg qftecditiq eikiirdtli atlngiyhqr iqypddkd